• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

减重手术后食管动力障碍的临床相关性:一项基于高分辨率阻抗测压法的前瞻性研究

CLINICAL RELEVANCE OF ESOPHAGEAL MOTILITY DISORDERS AFTER BARIATRIC SURGERY: A PROSPECTIVE STUDY BASED ON HIGH-RESOLUTION IMPEDANCE MANOMETRY.

作者信息

Difante Lucas Dos Santos, Trindade Eduardo Neubarth, Lopes Antonio de Barros, Martins Eduardo Ferreira, Remus Isadora Bosini, Trindade Manoel Roberto Maciel

机构信息

Universidade Federal do Rio Grande do Sul, Hospital de Clínicas de Porto Alegre, Department of Digestive Surgery - Porto Alegre (RS), Brazil.

Universidade Federal do Rio Grande do Sul, Hospital de Clínicas de Porto Alegre, Department of Gastroenterology - Porto Alegre (RS), Brazil.

出版信息

Arq Bras Cir Dig. 2024 Dec 2;37:e1842. doi: 10.1590/0102-6720202400048e1842. eCollection 2024.

DOI:10.1590/0102-6720202400048e1842
PMID:39630843
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11654458/
Abstract

BACKGROUND

There is recent evidence showing that obesity is associated with gastroesophageal reflux disease and esophageal dysmotility, although symptoms are not always present.

AIMS

This is a prospective study based on high-resolution manometry findings in bariatric surgery candidates and their correlation with postoperative dysphagia.

METHODS

Manometric evaluation was performed on candidates for bariatric surgery from 2022 to 2024. The examination was conducted according to the protocol of the fourth version of the Chicago Classification, including different positions and provocative maneuvers to confirm the diagnosis of dysmotility. Patients were followed for 90 days after surgery to verify the occurrence of dysphagia or difficulty adapting to the diet.

RESULTS

High-resolution manometry was performed on 46 candidates for bariatric surgery with a mean body mass index of 46.5 kg/m2. Esophagogastric junction outflow obstruction was diagnosed in 16 (34.8%) patients, and ineffective esophageal motility was diagnosed in 8 (17.4%) patients. None of the subjects reported symptoms during the preoperative period. Out of the 46 individuals initially included, 44 underwent bariatric surgery, 23 (52.3%) underwent Roux-en-Y gastric bypass, and 21 (47.7%) underwent sleeve gastrectomy. One patient with esophagogastric junction outflow obstruction reported dysphagia after Roux-en-Y bypass, but symptoms spontaneously resolved during the 90-day follow-up period.

CONCLUSIONS

Although patients with severe obesity have a high prevalence of esophageal motility disorders, no clinical repercussions were observed after bariatric surgery during the study period.

摘要

背景

最近有证据表明,肥胖与胃食管反流病及食管动力障碍有关,尽管并非总是出现症状。

目的

这是一项基于对肥胖症手术候选者进行高分辨率测压结果及其与术后吞咽困难相关性的前瞻性研究。

方法

对2022年至2024年肥胖症手术候选者进行测压评估。检查按照芝加哥分类第四版方案进行,包括不同体位和激发动作以确诊动力障碍。术后对患者随访90天,以核实吞咽困难或饮食适应困难的发生情况。

结果

对46例肥胖症手术候选者进行了高分辨率测压,平均体重指数为46.5kg/m²。16例(34.8%)患者被诊断为食管胃交界部流出道梗阻,8例(17.4%)患者被诊断为食管动力无效。术前所有受试者均未报告症状。最初纳入的46人中,44人接受了肥胖症手术,23例(52.3%)接受了Roux-en-Y胃旁路手术,21例(47.7%)接受了袖状胃切除术。1例食管胃交界部流出道梗阻患者在Roux-en-Y旁路手术后出现吞咽困难,但在90天随访期内症状自行缓解。

结论

尽管重度肥胖患者食管动力障碍患病率较高,但在研究期间肥胖症手术后未观察到临床不良反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f713/11654458/372729d6b97e/0102-6720-abcd-37-e1842-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f713/11654458/6adb1b030660/0102-6720-abcd-37-e1842-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f713/11654458/372729d6b97e/0102-6720-abcd-37-e1842-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f713/11654458/6adb1b030660/0102-6720-abcd-37-e1842-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f713/11654458/372729d6b97e/0102-6720-abcd-37-e1842-gf02.jpg

相似文献

1
CLINICAL RELEVANCE OF ESOPHAGEAL MOTILITY DISORDERS AFTER BARIATRIC SURGERY: A PROSPECTIVE STUDY BASED ON HIGH-RESOLUTION IMPEDANCE MANOMETRY.减重手术后食管动力障碍的临床相关性:一项基于高分辨率阻抗测压法的前瞻性研究
Arq Bras Cir Dig. 2024 Dec 2;37:e1842. doi: 10.1590/0102-6720202400048e1842. eCollection 2024.
2
Postobesity Surgery Esophageal Dysfunction: A Combined Cross-Sectional Prevalence Study and Retrospective Analysis.肥胖手术后食管功能障碍:一项联合横断面患病率研究和回顾性分析。
Am J Gastroenterol. 2020 Oct;115(10):1669-1680. doi: 10.14309/ajg.0000000000000733.
3
Breakthrough Contractions During Multiple Rapid Swallows on High-Resolution Esophageal Manometry: A Marker of Esophageal Dysmotility in Post-Bariatric Surgery Patients.高分辨率食管测压中多次快速吞咽时的突破性收缩:减重手术后患者食管运动障碍的一个标志物
Obes Surg. 2025 Jan;35(1):154-160. doi: 10.1007/s11695-024-07604-8. Epub 2024 Dec 10.
4
High-resolution Impedance Manometry after Sleeve Gastrectomy: Increased Intragastric Pressure and Reflux are Frequent Events.袖状胃切除术后的高分辨率阻抗测压法:胃内压力升高和反流是常见情况。
Obes Surg. 2016 Oct;26(10):2449-56. doi: 10.1007/s11695-016-2127-y.
5
Characterization and follow-up of esophagogastric junction outflow obstruction detected by high resolution manometry.高分辨率测压法检测食管胃交界部流出道梗阻的特征及随访
Neurogastroenterol Motil. 2016 Jan;28(1):116-26. doi: 10.1111/nmo.12708. Epub 2015 Oct 30.
6
Derangement of esophageal anatomy and motility in morbidly obese patients: a prospective study based on high-resolution impedance manometry.肥胖症患者食管解剖和运动功能障碍:基于高分辨率阻抗测压法的前瞻性研究。
Surg Obes Relat Dis. 2020 Dec;16(12):2006-2015. doi: 10.1016/j.soard.2020.07.023. Epub 2020 Aug 1.
7
High-resolution manometry in the upright position could improve the manometric evaluation of morbidly obese patients with esophagogastric junction outflow obstruction.直立位高分辨率测压可改善胃食管交界处流出梗阻的病态肥胖患者的测压评估。
Neurogastroenterol Motil. 2020 Nov;32(11):e13924. doi: 10.1111/nmo.13924. Epub 2020 Jun 29.
8
Gastric banding interferes with esophageal motility and gastroesophageal reflux.胃束带术会干扰食管动力和胃食管反流。
Arch Surg. 2005 Jul;140(7):639-43. doi: 10.1001/archsurg.140.7.639.
9
Spectrum of esophageal dysmotility in systemic sclerosis on high-resolution esophageal manometry as defined by Chicago classification.根据芝加哥分类法,系统性硬化症患者高分辨率食管测压下食管动力障碍的频谱。
Dis Esophagus. 2017 Dec 1;30(12):1-6. doi: 10.1093/dote/dox067.
10
Normative high resolution esophageal manometry values in asymptomatic patients with obesity.无症状肥胖患者的正常高分辨率食管测压值。
Neurogastroenterol Motil. 2024 Nov;36(11):e14914. doi: 10.1111/nmo.14914. Epub 2024 Sep 17.

本文引用的文献

1
Impact of Body Composition on Esophagogastric Junction Opening Measures: Discordant FLIP and Manometric Findings Are More Common With Increased Body Mass Index.身体成分对食管胃交界部开放指标的影响:随着体重指数增加,功能性腔内成像探头检查(FLIP)和测压结果不一致的情况更常见。
Am J Gastroenterol. 2024 May 2. doi: 10.14309/ajg.0000000000002823.
2
Esophagogastric Junction Outflow Obstruction (EGJOO): A Manometric Phenomenon or Clinically Impactful Problem.食管胃结合部流出梗阻(EGJOO):一种测压学现象还是具有临床显著影响的问题。
Curr Gastroenterol Rep. 2024 Jul;26(7):173-180. doi: 10.1007/s11894-024-00928-6. Epub 2024 Mar 28.
3
LAPAROSCOPIC SLEEVE GASTRECTOMY VERSUS LAPAROSCOPIC ROUX-EN-Y GASTRIC BYPASS FOR WEIGHT LOSS IN OBESE PATIENTS: WHICH IS MORE EFFECTIVE? A SYSTEMATIC REVIEW AND META-ANALYSIS.
腹腔镜袖状胃切除术与腹腔镜胃旁路术治疗肥胖患者体重减轻的效果比较:哪种更有效?系统评价和荟萃分析。
Arq Bras Cir Dig. 2023 Dec 8;36:e1782. doi: 10.1590/0102-672020230064e1782. eCollection 2023.
4
NEW CLASSIFICATION FOR ESOPHAGEAL MOTILITY DISORDERS (CHICAGO CLASSIFICATION VERSION 4.0©) AND CHAGAS DISEASE ESOPHAGOPATHY (ACHALASIA).食管动力障碍的新分类(芝加哥分类第4.0版©)与恰加斯病食管病变(贲门失弛缓症)。
Arq Bras Cir Dig. 2022 Jan 31;34(4):e1624. doi: 10.1590/0102-672020210002e1624. eCollection 2022.
5
Esophagogastric junction outflow obstruction.食管胃交界部流出道梗阻
Neurogastroenterol Motil. 2021 Sep;33(9):e14193. doi: 10.1111/nmo.14193. Epub 2021 Jun 12.
6
Manometric changes of the esophagus in morbidly obese patients.病态肥胖患者食管的测压变化
Exp Ther Med. 2021 Jun;21(6):604. doi: 10.3892/etm.2021.10036. Epub 2021 Apr 14.
7
US national trends in bariatric surgery: A decade of study.美国肥胖症手术的国家趋势:十年研究。
Surgery. 2021 Jul;170(1):13-17. doi: 10.1016/j.surg.2021.02.002. Epub 2021 Mar 11.
8
Esophageal motility disorders on high-resolution manometry: Chicago classification version 4.0.高分辨率食管动力障碍:芝加哥分类版本 4.0。
Neurogastroenterol Motil. 2021 Jan;33(1):e14058. doi: 10.1111/nmo.14058.
9
Multiple rapid swallows and rapid drink challenge in patients with esophagogastric junction outflow obstruction on high-resolution manometry.高分辨率测压时食管胃结合部流出梗阻患者多次快速吞咽和快速饮挑战。
Neurogastroenterol Motil. 2021 Mar;33(3):e14000. doi: 10.1111/nmo.14000. Epub 2020 Oct 11.
10
Derangement of esophageal anatomy and motility in morbidly obese patients: a prospective study based on high-resolution impedance manometry.肥胖症患者食管解剖和运动功能障碍:基于高分辨率阻抗测压法的前瞻性研究。
Surg Obes Relat Dis. 2020 Dec;16(12):2006-2015. doi: 10.1016/j.soard.2020.07.023. Epub 2020 Aug 1.