10月7日加沙战争爆发期间新诊断的多发性硬化症患者的创伤后应激障碍和抑郁症症状：来自约旦的一项病例对照研究

Symptoms of PTSD and depression in newly diagnosed people with multiple sclerosis during the outbreak Oct.7th war on Gaza: A case-control study from Jordan.

作者信息

Al-Ameri Mariam, Mansour Mohammad, Al-Habahbeh Suha, Weshah Feras, Ennab Wail, Gammoh Omar

机构信息

Department of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmacy, Yarmouk University, Irbid, Jordan.

Department of Neurology, Al-Bashir Hospital, Amman, Jordan.

出版信息

Mult Scler Relat Disord. 2025 Jan;93:106206. doi: 10.1016/j.msard.2024.106206. Epub 2024 Dec 1.

DOI:10.1016/j.msard.2024.106206

PMID:39631135

Abstract

The present study examined the severity and the correlates of post-traumatic stress disorder (PTSD) and depression symptoms severity in newly diagnosed people with multiple sclerosis (PwMS) compared to healthy people during the outbreak of the Oct.7th war on Gaza. This is a cross-sectional case-control study recruiting 63 PwMS and 79 controls. The severity of PTSD and depression were measured using validated scales. There was no significant (p>0.05) difference in PTSD and depression scores between the PwMS and the controls. In addition, PwMS who experienced one or more relapses since diagnosis were at a significantly higher risk (B=9.29, t=2.06, p=0.04) for severe PTSD and severe depressive (OR=5.50, 95% CI=1.32-22.92, p=0.01). The study of the mental health of PwMS during times of crisis is emerging in developing countries, future larger-scale and follow-up studies are yet required.

摘要

本研究调查了在10月7日加沙战争爆发期间，新诊断的多发性硬化症患者（PwMS）与健康人群相比，创伤后应激障碍（PTSD）的严重程度及其相关因素，以及抑郁症状的严重程度。这是一项横断面病例对照研究，招募了63名PwMS和79名对照。使用经过验证的量表测量PTSD和抑郁的严重程度。PwMS和对照组之间的PTSD和抑郁评分没有显著差异（p>0.05）。此外，自诊断以来经历过一次或多次复发的PwMS出现严重PTSD和严重抑郁的风险显著更高（B=9.29, t=2.06, p=0.04）（OR=5.50, 95% CI=1.32 - 22.92, p=0.01）。发展中国家正在开展关于危机时期PwMS心理健康状况的研究，未来仍需要更大规模的后续研究。