Andy Uduak U, Newman Diane K, Wyman Jean F, Klusaritz Heather, Walsh Wendy, Shou Haochang, Koepler Nathanael, Schmitz Kathryn H, Reaves Simone, Arya Lily, Brown Rebecca T
Department of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, USA.
Department of Surgery, University of Pennsylvania, Philadelphia, USA.
BMC Geriatr. 2024 Dec 4;24(1):994. doi: 10.1186/s12877-024-05552-7.
Urgency urinary incontinence (UUI), a risk factor for falls, affects 40% of women over the age of 70 years. Multicomponent interventions have the potential to decrease the risk of falls and urinary symptoms in women. We previously designed and conducted a pilot study of a multicomponent, theory-driven intervention in women with UUI. The Mobility and Voiding Exercises in Older Women with Urinary Incontinence (MoVEonUp) Trial will assess the efficacy of this intervention to decrease falls and urinary incontinence in community-dwelling older women.
In the MoVEonUp Trial, 314 women ages ≥ 70 years with UUI will be randomized to the intervention group or an attention control group. Women randomized to the intervention will participate in a home-based multicomponent program consisting of strength and balance training, bladder training with urge suppression strategies, and a home hazard assessment by an occupational therapist. Women in the control group will receive an educational booklet on falls prevention and behavioral treatment for urinary incontinence. Outcomes of falls, urinary incontinence, physical function, functional limitations, and mobility will be measured at 3, 6, 9, and 12 months.
This study will determine if a home-based multicomponent program reduces the risk of falls and improves incontinence among older women with UUI. If the intervention is efficacious, it will help address the critical need to reduce falls in this population via an intervention that can be implemented in the home setting.
NCT05375344.
急迫性尿失禁（UUI）是跌倒的一个风险因素，影响着40%的70岁以上女性。多组分干预措施有可能降低女性跌倒风险和改善泌尿症状。我们之前设计并开展了一项针对患有UUI的女性的多组分、理论驱动干预措施的试点研究。老年女性尿失禁患者的移动与排尿锻炼（MoVEonUp）试验将评估该干预措施对减少社区居住老年女性跌倒和尿失禁的疗效。
在MoVEonUp试验中，314名年龄≥70岁且患有UUI的女性将被随机分配到干预组或注意力控制组。随机分配到干预组的女性将参与一项居家多组分项目，该项目包括力量和平衡训练、采用尿急抑制策略的膀胱训练以及由职业治疗师进行的家庭危险因素评估。对照组的女性将收到一本关于预防跌倒和尿失禁行为治疗的教育手册。将在3个月、6个月、9个月和12个月时测量跌倒、尿失禁、身体功能、功能受限和活动能力等结果。
本研究将确定一项居家多组分项目是否能降低患有UUI的老年女性的跌倒风险并改善尿失禁情况。如果该干预措施有效，它将有助于通过一项可在家庭环境中实施的干预措施来满足减少该人群跌倒这一迫切需求。
NCT05375344。
