Brune Daniela, Stojanov Thomas, Müller Andreas Marc, Weibel David, Hunziker Sabina, Erdbrink Stephanie, Audigé Laurent
Schulthess Klinik, Research and Development Department - Shoulder and Elbow Surgery, Zurich, Switzerland.
Faculty of Psychology, UniDistance Suisse, Brig, Switzerland.
BMC Musculoskelet Disord. 2024 Dec 4;25(1):992. doi: 10.1186/s12891-024-08099-1.
Assessing health-related quality of life (HRQoL) is a widely employed method in orthopedics to evaluate patient well-being and measure the effectiveness of surgical interventions. Understanding the relationship between specific baseline factors and preoperative HRQoL can help clinicians identify patients at risk for low quality of life and thus, develop preventive strategies that adequately address individual patient needs. The objective was to assess associations between baseline factors and preoperative HRQoL in patients undergoing arthroscopic rotator cuff repair (ARCR).
This study is part of a multicenter prospective Swiss cohort study that included patients undergoing ARCR between June 2020 and November 2021. Data were derived from baseline and surgery forms. HRQoL was assessed using the European Quality of Life 5-Dimension 5-Level (EQ-5D-5L) questionnaire to calculate EQ-5D index and EQ VAS scores. Univariable and multivariable linear regression models examined associations between the 21 factors and preoperative HRQoL. Final models were determined using stepwise backward regression.
A total of 973 included patients (mean age [SD], 57.3 [9.4] years; 611 men [63%]) had a mean [SD] EQ-5D index and EQ VAS of 0.70 [0.23] and 68.7 [19.8], respectively. Being male (regression coefficient (β), 0.05; 95% CI [0.02-0.08]), having a higher age (β, 0.02; 95% CI [0.01-0.03]) and higher education levels (e.g., university, college: β, 0.11; 95% CI [0.06-0.16]) were associated with a higher EQ-5D index. Increased body mass index (β, -0.02; 95% CI [-0.04 to -0.01]) and worse sleep quality (β, -0.03; 95% CI [-0.04 to -0.03]) were associated with a lower EQ-5D index. Factors negatively associated with overall EQ VAS health were depression (e.g., moderate: β, -12.70; 95% CI [-16.18 to -9.21]), presence of at least one comorbidity (β, -3.71; 95% CI [-5.91 to -1.52]), and pain (β, -1.81; 95% CI [-2.36 to -1.26]).
Our results suggest that preoperative HRQoL is highly associated with sociodemographic and patient-related factors. Specifically addressing these factors may improve orthopedic care.
评估健康相关生活质量(HRQoL)是骨科广泛采用的一种方法,用于评估患者的健康状况并衡量手术干预的效果。了解特定基线因素与术前HRQoL之间的关系有助于临床医生识别生活质量低下风险的患者,从而制定能够充分满足个体患者需求的预防策略。目的是评估关节镜下肩袖修复术(ARCR)患者的基线因素与术前HRQoL之间的关联。
本研究是一项多中心前瞻性瑞士队列研究的一部分,纳入了2020年6月至2021年11月期间接受ARCR的患者。数据来自基线和手术表格。使用欧洲生活质量五维度五级(EQ-5D-5L)问卷评估HRQoL,以计算EQ-5D指数和EQ VAS评分。单变量和多变量线性回归模型检验了21个因素与术前HRQoL之间的关联。最终模型采用逐步向后回归确定。
总共973名纳入患者(平均年龄[标准差],57.3[9.4]岁;611名男性[63%])的平均[标准差]EQ-5D指数和EQ VAS分别为0.70[0.23]和68.7[19.8]。男性(回归系数(β),0.05;95%置信区间[0.02 - 0.08])、年龄较大(β,0.02;95%置信区间[0.01 - 0.03])和教育水平较高(如大学、大专:β,0.11;95%置信区间[0.06 - 0.16])与较高的EQ-5D指数相关。体重指数增加(β,-0.02;95%置信区间[-0.04至-0.01])和睡眠质量较差(β,-0.03;95%置信区间[-0.04至-0.03])与较低的EQ-5D指数相关。与总体EQ VAS健康呈负相关的因素包括抑郁(如中度:β,-12.70;95%置信区间[-16.18至-9.21])、存在至少一种合并症(β,-3.71;95%置信区间[-5.91至-1.52])和疼痛(β,-1.81;95%置信区间[-2.36至-1.26])。
我们的结果表明,术前HRQoL与社会人口统计学和患者相关因素高度相关。具体解决这些因素可能会改善骨科护理。