Oliveira Rita R, Pereira Ana, Costa Pedro, Ferreira Ana
Anesthesiology, Hospital Vila Franca de Xira, Lisboa, PRT.
Cureus. 2024 Dec 3;16(12):e75033. doi: 10.7759/cureus.75033. eCollection 2024 Dec.
Familial amyloid polyneuropathy type I is a rare neurodegenerative disease characterised by early-onset and progressive peripheral sensorimotor and autonomic polyneuropathy. A pregnant woman with familial amyloid polyneuropathy type I presented with mild gastrointestinal, cardiac involvement and peripheral neuropathy, aggravated during the pregnancy. The caesarean delivery was performed under uneventful epidural anaesthesia. Anaesthesia of a pregnant woman with this condition can be challenging due to its multisystemic involvement and the possibility of further neurologic injury. This is one of the few cases of anaesthesia for caesarean section described in familial amyloid polyneuropathy type I patients. Given the possibility of similar cases, it is essential to disclose the anaesthetic management.
I型家族性淀粉样多神经病是一种罕见的神经退行性疾病，其特征为早发性和进行性周围感觉运动及自主神经多神经病。一名患有I型家族性淀粉样多神经病的孕妇出现轻度胃肠道、心脏受累及周围神经病变，在孕期病情加重。剖宫产在平稳的硬膜外麻醉下进行。由于该疾病涉及多系统且有进一步神经损伤的可能性，为患有这种疾病的孕妇实施麻醉具有挑战性。这是为数不多的关于I型家族性淀粉样多神经病患者剖宫产麻醉的病例之一。鉴于可能存在类似病例，披露麻醉管理情况至关重要。
