Padma Adla, Ramaiah Mangayarkarasi
School of Computer Science Engineering and Information systems, Vellore Institute of Technology, Vellore, India.
Heliyon. 2024 Nov 8;10(22):e40273. doi: 10.1016/j.heliyon.2024.e40273. eCollection 2024 Nov 30.
Pharmaceutical supply chain management (PSCM) aims to alleviate logistical challenges. However, traditional online pharma systems face issues during implementation, particularly regarding transparency and fostering mutual trust among stakeholders. The primary security goals for a supply chain management (SCM) solution are ensuring authentication, confidentiality, data provenance, and auditability. The proposed blockchain-based solution (BPSCM) is implemented in three phases: registration, pharmaceutical product circulation, and secure payment. The registration phase computes the identification number upon the hashed private key along with the Edwards-curve digital signature algorithm (EdDSA) for all the stakeholders. The pharm product circulation phase implements the transactions among the participants by developing smart contracts where cryptographic operators ensure data provenance. The security analysis demonstrates that the framework effectively mitigates impersonation and collusion attacks. Performance metrics, including gas consumption, throughput, latency, and computational cost, were examined and compared to standard PSCM frameworks to evaluate the BPSCM's effectiveness.
药品供应链管理（PSCM）旨在缓解物流挑战。然而，传统的在线制药系统在实施过程中面临问题，特别是在透明度以及促进利益相关者之间的相互信任方面。供应链管理（SCM）解决方案的主要安全目标是确保认证、保密性、数据来源和可审计性。所提出的基于区块链的解决方案（BPSCM）分三个阶段实施：注册、药品流通和安全支付。注册阶段为所有利益相关者根据哈希后的私钥以及爱德华兹曲线数字签名算法（EdDSA）计算识别号。药品流通阶段通过开发智能合约来实现参与者之间的交易，其中加密运算符确保数据来源。安全分析表明，该框架有效地减轻了身份冒用和勾结攻击。研究了包括燃气消耗、吞吐量、延迟和计算成本在内的性能指标，并与标准PSCM框架进行比较，以评估BPSCM的有效性。
