Al Yazidi Laila, Almughaizwi Tahani, Al Maamari Khuloud, Al Farsi Fatma, Abdellatif Mohamed, Al Shibli Naema
Department of Child Health.
Oman Medical Speciality Board, Muscat, Oman.
Sultan Qaboos Univ Med J. 2024 Nov;24(4):523-527. doi: 10.18295/squmj.11.2024.070. Epub 2024 Nov 27.
Little is known about the profile of perinatal infections among abandoned neonates, and there are no specific evidence-based guidelines on how to screen and manage these neonates. This study aimed to report the rate of perinatal infections among abandoned babies managed at Sultan Qaboos University Hospital (SQUH), Muscat, Oman, over 15 years (2006-2021).
This retrospective cohort study included all abandoned babies admitted at SQUH from January 2006 to December 2021. Demographic data, the area where they were found, anthropometric parameters, symptoms, investigations and management were included in the study.
Of the 20 neonates included in this study, 11 (55%) were male and 9 (45%) were female; only 1 baby looked preterm. The estimated median age at admission was 1 day, while the median length of hospitalisation was 30 days. Infectious disease screening was not optimal for syphilis. Among the babies who were tested for perinatal infections such as HIV (n = 20), syphilis (n = 7), hepatitis B (n = 20) and hepatitis C (n = 19), none tested positive and all babies received the hepatitis B vaccine. Overall, 13 out of 20 babies received antibiotics for presumed sepsis. Zidovudine was given prophylactically to 3 neonates until the HIV test result was received. A total of 2 neonates were managed for gastroenteritis, 2 for sepsis and 1 for pneumonia; no death was recorded.
A national protocol on what should be included in the screening and how to manage these babies is urgently needed to avoid adverse outcomes in this disadvantaged population.
关于弃婴围产期感染情况知之甚少,且对于如何筛查和管理这些新生儿尚无基于证据的具体指南。本研究旨在报告阿曼马斯喀特苏丹卡布斯大学医院(SQUH)在15年期间(2006 - 2021年)收治的弃婴中围产期感染的发生率。
这项回顾性队列研究纳入了2006年1月至2021年12月在SQUH收治的所有弃婴。研究包括人口统计学数据、发现弃婴的地点、人体测量参数、症状、检查及管理情况。
本研究纳入的20例新生儿中,11例(55%)为男性,9例(45%)为女性;只有1例婴儿看起来为早产儿。入院时估计的中位年龄为1天,而中位住院时间为30天。梅毒的传染病筛查并不理想。在接受围产期感染检测的婴儿中,如艾滋病毒(n = 20)、梅毒(n = 7)、乙型肝炎(n = 20)和丙型肝炎(n = 19),均无检测呈阳性者,所有婴儿均接种了乙肝疫苗。总体而言,20例婴儿中有13例因疑似败血症接受了抗生素治疗。3例新生儿预防性给予了齐多夫定,直至收到艾滋病毒检测结果。共有2例新生儿接受了胃肠炎治疗,2例接受了败血症治疗,1例接受了肺炎治疗;无死亡记录。
迫切需要制定一项关于筛查应涵盖哪些内容以及如何管理这些婴儿的国家方案,以避免这一弱势群体出现不良后果。