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针对性生活方式干预对中青年高血压患者脑功能的影响:一项回顾性队列分析。

The impact of targeted lifestyle interventions on brain function in young and middle-aged patients with hypertension: A retrospective cohort analysis.

作者信息

Yu Yangjie, Chen Qiying

机构信息

Yangjie Yu, Department of Cardiology, Huashan Hospital, Fudan University, Shanghai, 200040, P.R. China.

Qiying Chen, Department of Cardiology, Huashan Hospital, Fudan University, Shanghai, 200040, P.R. China.

出版信息

Pak J Med Sci. 2024 Dec;40(11):2588-2593. doi: 10.12669/pjms.40.11.10304.

Abstract

OBJECTIVE

To explore the impact of targeted lifestyle interventions on brain function in young and middle-aged patients with hypertension.

METHODS

Clinical data of 104 young and middle-aged patients with hypertension, treated in Huashan Hospital, Fudan University from June 2021 to September 2023, were retrospectively analyzed. Forty nine patients received routine nursing care (control group), and 55 patients received targeted lifestyle interventions in addition to routine nursing care (observation group). Blood pressure levels, cognitive function, memory function, executive function, and working memory ability were compared between the two groups before and after the intervention.

RESULTS

After the intervention, blood pressure levels in both groups decreased compared to before the intervention, and were significantly lower in the observation group compared to the control group (<0.05). After the intervention, both groups showed significant improvements in cognitive function, memory function, executive function, and working memory ability (<0.05).

CONCLUSIONS

Targeted lifestyle interventions can significantly improve blood pressure control levels and brain function in young and middle-aged patients with hypertension.

摘要

目的

探讨针对性生活方式干预对中青年高血压患者脑功能的影响。

方法

回顾性分析2021年6月至2023年9月在复旦大学附属华山医院接受治疗的104例中青年高血压患者的临床资料。49例患者接受常规护理(对照组),55例患者在常规护理基础上接受针对性生活方式干预(观察组)。比较两组干预前后的血压水平、认知功能、记忆功能、执行功能和工作记忆能力。

结果

干预后,两组血压水平均较干预前下降,且观察组显著低于对照组(<0.05)。干预后,两组认知功能、记忆功能、执行功能和工作记忆能力均有显著改善(<0.05)。

结论

针对性生活方式干预可显著提高中青年高血压患者的血压控制水平和脑功能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/391d/11613360/8eea0a72db1c/PJMS-40-2588-g001.jpg

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