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一名Ⅰ型成骨不全患者产后多发性椎体骨折:病例报告及文献综述

Postpartum multiple vertebral fractures in a patient with osteogenesis imperfecta type I: A case report and literature review.

作者信息

Miyazaki Yumiko, Hosokawa Mizuki, Kudo Sho, Onuma Toshimichi, Orisaka Makoto, Yoshida Yoshio

机构信息

Department of Obstetrics and Gynecology, Faculty of Medical Sciences, University of Fukui, Japan.

出版信息

Case Rep Womens Health. 2024 Nov 16;44:e00666. doi: 10.1016/j.crwh.2024.e00666. eCollection 2024 Dec.

Abstract

A 39-year-old woman with type I osteogenesis imperfecta reported experiencing back pain at 35 weeks of gestation. Two days following an elective cesarean section, the patient developed a Th12 vertebral compression fracture; 3 weeks postoperatively, she sustained an L3 vertebral compression fracture. The patient displayed a lumbar spine -score of -1.7; she subsequently discontinued breastfeeding, and treatment with active vitamin D was initiated. Genetic testing confirmed a diagnosis of osteogenesis imperfecta.

摘要

一名患有I型成骨不全症的39岁女性在妊娠35周时出现背痛。择期剖宫产术后两天,该患者发生了第12胸椎椎体压缩性骨折;术后3周,她又出现了第3腰椎椎体压缩性骨折。患者腰椎骨密度T值为-1.7;随后她停止母乳喂养,并开始使用活性维生素D进行治疗。基因检测确诊为成骨不全症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96ae/11616087/6ba3952c147f/gr1.jpg

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