Orton E C, Polher O, Shenk R, Hohn R B
Am J Vet Res. 1986 Mar;47(3):677-82.
Bilateral midshaft femoral osteotomies were fixed with a 3-mm fracture gap in 6 dogs. In each dog, one femur was fixed with a porous titanium-surfaced bone plate and screws, whereas the opposite femur was fixed with a standard smooth-surfaced bone plate and screws. The mean removal torque for porous titanium-surfaced screws (32.3 kg X cm) was significantly (P less than 0.01) greater than the mean removal torque for standard screws (4.4 kg X cm). Osseous tissue ingrowth into the surface of porous titanium-surfaced screws was verified by histologic examination of the bone-screw interface. Radiographic and histologic examinations of the osteotomy gaps showed accelerated primary gap healing in osteotomies fixed with porous titanium-coated implants, compared with slower callus healing seen in osteotomies fixed with standard smooth-surfaced implants.
对6只犬进行双侧股骨干中段截骨术,截骨间隙为3毫米。每只犬的一侧股骨用多孔钛表面骨板和螺钉固定,而另一侧股骨用标准光滑表面骨板和螺钉固定。多孔钛表面螺钉的平均取出扭矩(32.3千克×厘米)显著高于标准螺钉的平均取出扭矩(4.4千克×厘米)(P<0.01)。通过对骨-螺钉界面的组织学检查证实骨组织长入多孔钛表面螺钉的表面。截骨间隙的影像学和组织学检查显示,与用标准光滑表面植入物固定的截骨术相比,用多孔钛涂层植入物固定的截骨术的一期间隙愈合加速,骨痂愈合较慢。