• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

接受非计划性切除的躯干和四肢软组织肉瘤的临床及影像学特征。

Clinical and radiologic features of soft tissue sarcoma in trunk and extremities that underwent unplanned excision.

作者信息

Seo Yujin, Yoon Young Cheol, Kim Hyun Su, Seo Sung Wook, Choi Yoon-La, Kim Kyunga, Lee Ji Hyun

机构信息

Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

Department of Orthopedic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

出版信息

PLoS One. 2024 Dec 5;19(12):e0311300. doi: 10.1371/journal.pone.0311300. eCollection 2024.

DOI:10.1371/journal.pone.0311300
PMID:39637150
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11620571/
Abstract

BACKGROUND

To identify the clinical and imaging characteristics of soft tissue sarcomas (STS) of the trunk and extremities that undergo unplanned excision.

METHODS

This retrospective study evaluated the data of patients with STS in the trunk or extremities between January 2008 and December 2021. Patients were divided into unplanned and planned excision groups based on their initial treatment. The distribution of histologic subtypes was analyzed, and the magnetic resonance imaging features were evaluated. Multivariable logistic regression was performed to identify variables independently associated with unplanned excision.

RESULTS

A total of 305 patients (mean age±standard deviation, 51±16.4 years; 179 males) were analyzed. The most prevalent subtype in the unplanned excision group was myxofibrosarcoma (22.3%). The unplanned excision group had a significantly smaller tumor size (p < 0.001) and more frequent superficial (p < 0.001) locations. Lobulated shape and peritumoral abnormalities were present in 70.0% and 50.0% of the unplanned excision group, respectively. Tumor size (adjusted odds ratio [OR], 0.87 per 1 cm increase; 95% confidence interval [CI], 0.77-0.98; p = 0.025) and superficial location (adjusted OR, 3.48; 95% CI, 1.57-7.72; p = 0.002) were independently associated with unplanned excision.

CONCLUSION

Myxofibrosarcoma is associated with a high frequency of unplanned excision. A significant number of patients in the unplanned excision group demonstrated a lobulated shape and peritumoral abnormalities. Only small tumor size and superficial location were independently associated with unplanned STS excision.

摘要

背景

确定接受非计划性切除的躯干和四肢软组织肉瘤（STS）的临床和影像学特征。

方法

这项回顾性研究评估了2008年1月至2021年12月期间躯干或四肢STS患者的数据。根据初始治疗情况将患者分为非计划性切除组和计划性切除组。分析组织学亚型的分布，并评估磁共振成像特征。进行多变量逻辑回归以确定与非计划性切除独立相关的变量。

结果

共分析了305例患者（平均年龄±标准差，51±16.4岁；男性179例）。非计划性切除组中最常见的亚型是黏液纤维肉瘤（22.3%）。非计划性切除组的肿瘤大小明显较小（p < 0.001），且更常见于浅表部位（p < 0.001）。非计划性切除组中分别有70.0%和50.0%的肿瘤呈分叶状和瘤周异常表现。肿瘤大小（调整后的优势比[OR]为每增加1 cm 0.87；95%置信区间[CI]为0.77 - 0.98；p = 0.025）和浅表部位（调整后的OR为3.48；95% CI为1.57 - 7.72；p = 0.002）与非计划性切除独立相关。

结论

黏液纤维肉瘤与非计划性切除的高频率相关。非计划性切除组中有相当数量的患者表现出分叶状和瘤周异常。只有小肿瘤大小和浅表部位与非计划性STS切除独立相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/39f5/11620571/e0252e693617/pone.0311300.g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/39f5/11620571/ea6ee31d9c64/pone.0311300.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/39f5/11620571/edbe122b4fd5/pone.0311300.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/39f5/11620571/77ead2c1f089/pone.0311300.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/39f5/11620571/e0252e693617/pone.0311300.g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/39f5/11620571/ea6ee31d9c64/pone.0311300.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/39f5/11620571/edbe122b4fd5/pone.0311300.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/39f5/11620571/77ead2c1f089/pone.0311300.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/39f5/11620571/e0252e693617/pone.0311300.g004.jpg

相似文献

1
Clinical and radiologic features of soft tissue sarcoma in trunk and extremities that underwent unplanned excision.接受非计划性切除的躯干和四肢软组织肉瘤的临床及影像学特征。
PLoS One. 2024 Dec 5;19(12):e0311300. doi: 10.1371/journal.pone.0311300. eCollection 2024.
2
Predictors of residual disease after unplanned excision of soft tissue sarcomas.软组织肉瘤意外切除术后残留疾病的预测因素。
J Surg Res. 2017 Feb;208:26-32. doi: 10.1016/j.jss.2016.08.096. Epub 2016 Sep 8.
3
Impact of residual disease after "unplanned excision" of primary localized adult soft tissue sarcoma of the extremities: evaluation of 452 cases at a single Institution.肢体原发性局限性成人软组织肉瘤“计划外切除”后残留疾病的影响：单机构452例病例评估
Musculoskelet Surg. 2017 Dec;101(3):243-248. doi: 10.1007/s12306-017-0475-y. Epub 2017 Apr 25.
4
MRI findings associated with microscopic residual tumor following unplanned excision of soft tissue sarcomas in the extremities.四肢软组织肉瘤计划外切除术后与微小残留肿瘤相关的MRI表现。
Skeletal Radiol. 2018 Feb;47(2):181-190. doi: 10.1007/s00256-017-2762-y. Epub 2017 Sep 1.
5
Influence of unplanned excisions on the outcomes of patients with stage III extremity soft-tissue sarcoma.计划性切缘外扩对 III 期肢体软组织肉瘤患者结局的影响。
Cancer. 2018 Oct 1;124(19):3868-3875. doi: 10.1002/cncr.31648. Epub 2018 Oct 15.
6
Comparative study of planned and unplanned excisions for the treatment of soft tissue sarcoma of the extremities.计划性与非计划性切除治疗肢体软组织肉瘤的对比研究
Clinics (Sao Paulo). 2014 Sep;69(9):579-84. doi: 10.6061/clinics/2014(09)01.
7
Pre-operative evaluation prior to soft tissue sarcoma excision - Why can't we get it right?软组织肉瘤切除术前评估——我们为何做不到位？
Eur J Surg Oncol. 2018 Feb;44(2):243-250. doi: 10.1016/j.ejso.2017.11.001. Epub 2017 Nov 20.
8
Radiomics model for predicting distant metastasis in soft tissue sarcoma of the extremities and trunk treated with surgery.用于预测接受手术治疗的四肢和躯干软组织肉瘤远处转移的放射组学模型。
Clin Transl Oncol. 2025 May;27(5):2307-2315. doi: 10.1007/s12094-024-03746-4. Epub 2024 Oct 1.
9
A comparison of clinical outcomes between additional excision after unplanned and planned excisions in patients with soft-tissue sarcoma of the limb : a propensity matching cohort study.肢体软组织肉瘤患者计划性和非计划性切除术后再次切除的临床结局比较：倾向评分匹配队列研究。
Bone Joint J. 2021 Dec;103-B(12):1809-1814. doi: 10.1302/0301-620X.103B12.BJJ-2021-0037.R1.
10
Do unplanned resections in soft tissue sarcomas of the extremities have an adverse impact on the prognosis? Experience of a Latin-American sarcoma reference center.肢体软组织肉瘤的非计划性切除是否会对预后产生不利影响？一家拉丁美洲肉瘤参考中心的经验。
Surg Oncol. 2025 Apr;59:102210. doi: 10.1016/j.suronc.2025.102210. Epub 2025 Mar 5.

本文引用的文献

1
S1-guideline cutaneous and subcutaneous leiomyosarcoma.S1 指南：皮肤和皮下平滑肌肉瘤。
J Dtsch Dermatol Ges. 2023 May;21(5):555-563. doi: 10.1111/ddg.14989. Epub 2023 Mar 31.
2
The Implications of an Unplanned Sarcoma Excision (the "Whoops" Operation).意外肉瘤切除术（“哎呀”手术）的影响
Surg Clin North Am. 2022 Aug;102(4):529-538. doi: 10.1016/j.suc.2022.04.002. Epub 2022 Jun 24.
3
Leiomyosarcoma: Current Clinical Management and Future Horizons.平滑肌肉瘤：当前临床管理与未来展望。
Surg Oncol Clin N Am. 2022 Jul;31(3):527-546. doi: 10.1016/j.soc.2022.03.011.
4
Incidence of unplanned excisions of soft tissue sarcomas in the Netherlands: A population-based study.荷兰软组织肉瘤意外切除的发生率：一项基于人群的研究。
Eur J Surg Oncol. 2022 May;48(5):994-1000. doi: 10.1016/j.ejso.2021.11.123. Epub 2021 Nov 19.
5
The incidence of unplanned excision in patients with soft tissue sarcoma: Reports from the Bone and Soft Tissue Tumor registry in Japan.软组织肉瘤患者计划性切缘不足的发生率：来自日本骨与软组织肿瘤登记处的报告。
J Orthop Sci. 2022 Mar;27(2):468-472. doi: 10.1016/j.jos.2020.12.025. Epub 2021 Feb 5.
6
The 2020 WHO Classification of Soft Tissue Tumours: news and perspectives.2020 年世界卫生组织软组织肿瘤分类：新闻与展望。
Pathologica. 2021 Apr;113(2):70-84. doi: 10.32074/1591-951X-213. Epub 2020 Nov 3.
7
Epithelioid sarcoma of the hand: a wolf in sheep's clothing.手部上皮样肉瘤：披着羊皮的狼。
J Plast Surg Hand Surg. 2021 Apr;55(2):96-104. doi: 10.1080/2000656X.2020.1838914. Epub 2020 Nov 11.
8
Soft-tissue sarcoma in adults: An update on the current state of histiotype-specific management in an era of personalized medicine.成人软组织肉瘤：在个体化医学时代，组织亚型特异性管理的最新进展。
CA Cancer J Clin. 2020 May;70(3):200-229. doi: 10.3322/caac.21605. Epub 2020 Apr 10.
9
Prognoses of superficial soft tissue sarcoma: The importance of fascia-tumor relationship on MRI.浅部软组织肉瘤的预后：MRI 中筋膜-肿瘤关系的重要性。
Eur J Surg Oncol. 2020 Feb;46(2):282-287. doi: 10.1016/j.ejso.2019.10.003. Epub 2019 Oct 5.
10
Development and Validation of Nomograms for Malignancy Prediction in Soft Tissue Tumors Using Magnetic Resonance Imaging Measurements.基于磁共振成像测量的软组织肿瘤恶性预测列线图的建立与验证。
Sci Rep. 2019 Mar 20;9(1):4897. doi: 10.1038/s41598-019-41230-0.