Harada A, Nakanuma Y, Govindarajan S, Peters R L
Ann Clin Lab Sci. 1986 Mar-Apr;16(2):155-62.
The clinical and the pathologic features of seven patients with nodular regenerative hyperplasia of the liver are analyzed and compared with those of 37 patients reported in the literature in an attempt to distinguish the features of those with portal hypertension from those without. Severe degrees of obliterative portal venopathy usually associated with the portal hypertension were found among the various pathological features. The association of nodular regenerative hyperplasia with a variety of chronic diseases suggests a heterogeneous group of pathogenic mechanisms. Our study reveals that only some of these mechanisms lead to the hepatic changes that cause portal hypertension.
分析了7例肝结节性再生性增生患者的临床和病理特征，并与文献报道的37例患者进行比较，试图区分有门静脉高压和无门静脉高压患者的特征。在各种病理特征中发现了通常与门静脉高压相关的严重程度的闭塞性门静脉病。结节性再生性增生与多种慢性疾病的关联提示了一组异质性的致病机制。我们的研究表明，只有其中一些机制会导致引起门静脉高压的肝脏变化。
