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手术之外:心理健康在乳房重建结果中的作用。

Beyond Surgery: Psychological Well-Being's Role in Breast Reconstruction Outcomes.

作者信息

Foppiani Jose, Lee Theodore C, Alvarez Angelica Hernandez, Escobar-Domingo Maria J, Taritsa Iulianna C, Lee Daniela, Schuster Kirsten, Wood Sasha, Utz Begum, Bai Christopher, Maranhao-Wong Lauren, Lee Bernard T

机构信息

Division of Plastic and Reconstructive Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.

Georgetown University, Washington, District of Columbia.

出版信息

J Surg Res. 2025 Jan;305:26-35. doi: 10.1016/j.jss.2024.10.040. Epub 2024 Dec 4.

Abstract

INTRODUCTION

Breast cancer is one of the most prevalent cancers worldwide, and following its treatment, many women turn to plastic surgery for reconstruction. A diagnosis of cancer is a heavy burden on patients. Yet, the effect of psychological/psychiatric comorbidities on patient satisfaction following their reconstruction remains unexplored. Thus, this paper aims to investigate how pre-existing psychological and psychiatric conditions impact patient-reported outcomes postreconstruction, compared to women without such conditions.

METHODS

A systematic review of PubMed, Web of Science, and Cochrane was completed. A qualitative synthesis of all included studies was then performed, and a subgroup analysis was then performed using a random effect model.

RESULTS

A total of 24 papers were included, encompassing a total population of 220,565 patients undergoing breast reconstruction between the ages of 18 and 84. The follow-up time ranged between 1.5 mo and 61 mo. In our study of breast reconstruction outcomes, the cohort with psychological/psychiatric comorbidities exhibited significant decreases in postoperative BREAST-Q scores compared to the control group: a 24-point [95% confidence interval (CI; -40, -8)] difference in satisfaction, a 20-point [95% CI (-57, -17)] difference in psychosocial well-being, an 18-point [95% CI (-28, 9)] difference in physical well-being, and a 33-point [95% CI (-51, -15)] difference in sexual well-being.

CONCLUSIONS

Ultimately, our analysis suggests that presurgical psychology status is a critical determinant of postsurgical patient-reported outcomes. These results encourage the development and inclusion of well-being screening and optimization prior to surgery as a mean to improve surgical outcomes.

摘要

引言

乳腺癌是全球最常见的癌症之一,在接受治疗后,许多女性会求助于整形手术进行重建。癌症诊断对患者来说是沉重的负担。然而,心理/精神共病对患者重建后满意度的影响仍未得到探索。因此,本文旨在研究与没有此类疾病的女性相比,术前存在的心理和精神状况如何影响重建后患者报告的结果。

方法

完成了对PubMed、科学网和Cochrane的系统评价。然后对所有纳入研究进行定性综合,并使用随机效应模型进行亚组分析。

结果

共纳入24篇论文,涵盖了年龄在18至84岁之间接受乳房重建的220,565名患者。随访时间在1.5个月至61个月之间。在我们对乳房重建结果的研究中,与对照组相比,患有心理/精神共病的队列术后BREAST-Q评分显著降低:满意度相差24分[95%置信区间(CI;-40,-8)],心理幸福感相差20分[95%CI(-57,-17)],身体幸福感相差18分[95%CI(-28,9)],性幸福感相差33分[95%CI(-51,-15)]。

结论

最终,我们的分析表明术前心理状态是术后患者报告结果的关键决定因素。这些结果鼓励在手术前开展并纳入幸福感筛查和优化,作为改善手术结果的一种手段。

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