Burato Arianna, Maruccio Giuseppe, Presutti Livio, Fernandez Ignacio Javier, Molteni Gabriele, Molinari Giulia
Department of Otolaryngology - Head and Neck Surgery, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Alma Mater Studiorum - Università di Bologna, Italy.
Department of Otolaryngology - Head and Neck Surgery, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Alma Mater Studiorum - Università di Bologna, Italy.
Cancer Treat Res Commun. 2024;42:100854. doi: 10.1016/j.ctarc.2024.100854. Epub 2024 Nov 26.
To review the published cases of meningioma en plaque of the temporal bone (TB-MEP), to gather evidence on the clinical assessment and management of this rare entity.
Following PRISMA statement recommendations, 383 abstracts were screened independently by two authors. Inclusion criteria were articles of human patients affected by TB-MEP; English or Italian language; availability of the abstract articles unrelated to TB-MEP, guidelines and systematic reviews were excluded. Only full-text articles reporting the diagnostic work-up and the management of the TB-MEP were considered for analysis.
A total of 12 articles were included, for a total of 25 patients with a mean age of 52 years (range: 31-71). The average time elapsed between the onset of symptoms and the actual diagnosis of TB-MEP was 36.5 months (range: 2-120). In most cases, the pathology presented with hearing loss (80 %), often accompanied by effusive otitis media (52 %), aural fullness (32 %), and tinnitus (32 %). The main Computed Tomography (CT) findings were hyperostosis (76 %), hairy appearance of bony margins (16 %), involvement of the mastoid and middle ear (48 %). Magnetic Resonance Imaging (MRI) revealed dural enhancement (28 %), temporal hyperostosis (20 %), a clearly enhancing extra-axial mass (28 %), compression of the surrounding vasculo-nervous structures (8 %) and the possible involvement of the temporal lobe (8 %). Forty percent of patients underwent various medical and surgical treatment before reaching the diagnosis. Forty-four percent of patients were sent to definitive surgical treatment, 44 % to follow-up while 8 % received radiotherapy.
Meningioma en plaque (MEP) is a rare tumour, particularly when it originates within the temporal bone. Appropriate imaging in patients complaining of audiological sign and symptoms is mandatory to avoid diagnostic delays, avoid inappropriate surgical procedures, and adopt the appropriate treatment.
回顾已发表的颞骨脑膜瘤斑块（TB-MEP）病例，收集有关这种罕见疾病临床评估和管理的证据。
按照PRISMA声明的建议，两位作者独立筛选了383篇摘要。纳入标准为受TB-MEP影响的人类患者的文章；英语或意大利语；摘要文章可供获取，与TB-MEP无关的文章、指南和系统评价被排除。仅考虑报告TB-MEP诊断检查和管理的全文文章进行分析。
共纳入12篇文章，涉及25例患者，平均年龄52岁（范围：31-71岁）。从症状出现到实际诊断TB-MEP的平均时间为36.5个月（范围：2-120个月）。在大多数情况下，病理学表现为听力损失（80%），常伴有渗出性中耳炎（52%）、耳闷（32%）和耳鸣（32%）。计算机断层扫描（CT）的主要表现为骨质增生（76%）、骨边缘毛糙（16%）、乳突和中耳受累（48%）。磁共振成像（MRI）显示硬脑膜强化（28%）、颞骨骨质增生（20%）、明显强化的轴外肿块（28%）、周围血管神经结构受压（8%）以及颞叶可能受累（8%）。40%的患者在确诊前接受了各种药物和手术治疗。44%的患者接受了确定性手术治疗，44%进行随访，8%接受了放疗。
脑膜瘤斑块（MEP）是一种罕见肿瘤，尤其是起源于颞骨时。对于有听力学症状的患者，进行适当的影像学检查对于避免诊断延误、避免不适当的手术操作以及采取适当的治疗至关重要。
