Pouly E, Biguenet A, Cholley P, Hocquet D, Bertrand X
Hygiène Hospitalière, Centre Hospitalier Universitaire, Besançon, France.
Hygiène Hospitalière, Centre Hospitalier Universitaire, Besançon, France; UMR 6249 Chrono-environnement, Université de Franche-Comté, Besançon, France.
J Hosp Infect. 2025 Feb;156:17-20. doi: 10.1016/j.jhin.2024.11.017. Epub 2024 Dec 3.
Staphylococcus haemolyticus is a clinically relevant coagulase-negative staphylococcus frequently responsible for hospital-acquired infections, especially in premature newborns.
To describe an outbreak of multidrug-resistant S. haemolyticus in a neonatal department.
The outbreak was investigated using classical methods, including screening of the patients, genotyping of the isolates and environmental survey. Numerous infection control measures were implemented.
In 2022 and 2023, a clonal outbreak of multidrug-resistant S. haemolyticus ST29 (40 infections and 71 carriages) occurred in the neonatology department of a University Hospital in France. The infection control measures implemented only partially controlled the outbreak. Although our investigation did not clearly identify the source and mode of transmission, a reservoir constituted by patients and transmission by healthcare workers are the most likely. This episode occurred in a context of countrywide outbreaks of S. haemolyticus ST29 in several French neonatology departments.
This prolonged outbreak of S. haemolyticus ST29 accounted for the increase in the incidence of S. haemolyticus-related infections in French neonatology departments. Implementation of proactive measures is crucial to limit the spread of such pathogens in neonatal ICUs.
溶血葡萄球菌是一种临床上具有重要意义的凝固酶阴性葡萄球菌，常导致医院获得性感染，尤其是在早产儿中。
描述新生儿科多药耐药溶血葡萄球菌的一次暴发。
采用经典方法对此次暴发进行调查，包括对患者进行筛查、对分离株进行基因分型以及进行环境调查。实施了多项感染控制措施。
2022年和2023年，法国一家大学医院的新生儿科发生了多药耐药溶血葡萄球菌ST29的克隆性暴发（40例感染和71例定植）。实施的感染控制措施仅部分控制了此次暴发。尽管我们的调查未明确确定传染源和传播方式，但最有可能的是由患者构成储存宿主并通过医护人员传播。这一事件发生在法国多个新生儿科出现溶血葡萄球菌ST29全国性暴发的背景下。
此次溶血葡萄球菌ST29的长期暴发导致法国新生儿科溶血葡萄球菌相关感染发病率上升。实施积极措施对于限制此类病原体在新生儿重症监护病房的传播至关重要。
