Suppr超能文献

保守治疗的肱骨近端骨折患者中QuickDASH、Constant评分和牛津肩评分之间的相关性及转换

Correlation and conversion between the QuickDASH, Constant Score, and Oxford Shoulder Score in patients with conservatively treated proximal humerus fractures.

作者信息

Chee Brian Rui Kye, Lim Chien Joo, Tan Bryan Yijia

机构信息

Department of Orthopaedic Surgery, Woodlands Health, Singapore.

Department of Orthopaedic Surgery, Woodlands Health, Singapore.

出版信息

J Shoulder Elbow Surg. 2025 Jul;34(7):e549-e556. doi: 10.1016/j.jse.2024.10.008. Epub 2024 Dec 3.

Abstract

BACKGROUND

There is significant heterogeneity of outcome measures used in the research of proximal humerus fractures (PHFs). Current evidence regarding the correlation and conversion between the various outcome measures is sparse. This study aims to study the correlation and conversion between the QuickDASH, Constant Score (CS), and Oxford Shoulder Score (OSS) in conservatively treated PHFs.

METHODS

A prospective cohort study of patients (n = 136) with conservatively treated PHFs between August 2017 and April 2020 was conducted. Patients had a minimum follow-up period of 1 year. The 3 outcome measures (QuickDASH, CS, and OSS) were collected at 4 time points-6 weeks, 3 months, 6 months, and 1 year after injury. Changes in scores across time and correlation between each pair of outcome measures were calculated. A linear regression model was used to derive conversion equations which were then internally validated.

RESULTS

A significant strong negative correlation was observed between the OSS and QuickDASH (coefficient: -0.746; P < .001), a significant moderate negative correlation was observed between the CS and QuickDASH (coefficient: -0.581; P < .001), and a significant moderate positive correlation was observed between the CS and OSS (coefficient: 0.697; P < .001). The 6 derived regression equations showed low mean differences between predicted and actual values (ranging from -1.21 to 2.51). The correlation between actual and predicted values was moderate to strong, ranging from a coefficient of 0.57 in the conversion from the CS to QuickDASH to 0.74 in the conversion from the CS to OSS and OSS to CS.

CONCLUSION

In a cohort of patients with conservatively managed PHFs, moderate to strong correlations were seen in pairwise comparisons of the OSS, QuickDASH, and CS. With linear regression analyses, 6 regression equations were derived to estimate one score from another. On internal validation, there was good agreement between the means of the predicted and actual scores but high within-individual variability. These formulae can help to compare studies with heterogeneous outcome measures and facilitate meta-analyses. However, these equations should not be used to predict one score from another in an individual due to variability when converting individual scores.

摘要

背景

肱骨近端骨折(PHFs)研究中使用的结局指标存在显著异质性。目前关于各种结局指标之间的相关性及转换的证据稀少。本研究旨在探讨保守治疗的PHFs患者中QuickDASH、Constant评分(CS)和牛津肩评分(OSS)之间的相关性及转换关系。

方法

对2017年8月至2020年4月间136例接受保守治疗的PHFs患者进行前瞻性队列研究。患者的最短随访期为1年。在受伤后6周、3个月、6个月和1年这4个时间点收集3种结局指标(QuickDASH、CS和OSS)。计算各时间点评分的变化以及每对结局指标之间的相关性。使用线性回归模型推导转换方程,然后进行内部验证。

结果

观察到OSS与QuickDASH之间存在显著的强负相关(系数:-0.746;P <.001),CS与QuickDASH之间存在显著的中度负相关(系数:-0.581;P <.001),CS与OSS之间存在显著的中度正相关(系数:0.697;P <.001)。推导得到的6个回归方程显示预测值与实际值之间的平均差异较小(范围为-1.21至2.51)。实际值与预测值之间的相关性为中度至强,从CS转换为QuickDASH时的系数为0.57,到CS转换为OSS以及OSS转换为CS时的系数为0.74。

结论

在保守治疗的PHFs患者队列中,OSS、QuickDASH和CS的两两比较显示出中度至强的相关性。通过线性回归分析,推导得到6个回归方程以从一个评分估算另一个评分。经内部验证,预测评分与实际评分的均值之间具有良好的一致性,但个体内变异性较高。这些公式有助于比较采用异质性结局指标的研究并促进荟萃分析。然而,由于转换个体评分时存在变异性,这些方程不应被用于预测个体的一个评分。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验