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接受抗凝或抗血小板治疗的髋部骨折患者的围手术期管理。SEDAR止血分会的共识性建议。

Perioperative management of the patients with hip fracture under anticoagulant or antiaggregants treatment. Consensus recommendations from the hemostasis section of SEDAR.

作者信息

Cassinello C, Ferrandis R, Gómez-Luque A, Hidalgo F, Llau J V, Yanes-Vidal G, Sierra P

机构信息

Servicio de Anestesiología, Reanimación y Tratamiento del Dolor, Hospital Universitario Infanta Sofía, Universidad Europea de Madrid, Madrid, Spain.

Servicio de Anestesiología, Reanimación y Tratamiento del Dolor, Hospital Clínic i Universitari La Fe, Universitat de València, Valencia, Spain.

出版信息

Rev Esp Anestesiol Reanim (Engl Ed). 2025 Jan;72(1):501651. doi: 10.1016/j.redare.2024.501651. Epub 2024 Dec 3.

Abstract

BACKGROUND

Antiaggregant and anticoagulant therapy complicate the management of patients with osteoporotic hip fracture.

OBJECTIVE

To homogenize and improve daily clinical practice with simple recommendations.

METHODS

The haemostasis section of SEDAR established a working group to define an action plan for the management of antiaggregated or anticoagulated patients with an osteoporotic hip fracture. The suggested recommendations are based on evidence of best practices, and have been validated by a multidisciplinary group formed by 6 specialties.

RESULTS

Early surgery reduces complications and mortality and improves patient comfort and functional recovery, with no difference in mortality between intradural and general anaesthesia.

CONCLUSION

Although uncertainties remain, it is recommended to perform surgery within 24-48 h of admission, adapting peripheral nerve blocks and type of anaesthesia (neuraxial or general) an to the haemostatic conditions. A multimodal management of antithrombotics, and the optimisation of haemostasis, haemoglobin and venous thromboprophylaxis since admission are suggested.

摘要

背景

抗血小板和抗凝治疗使骨质疏松性髋部骨折患者的管理变得复杂。

目的

通过简单的建议使日常临床实践同质化并得到改善。

方法

SEDAR的止血部门成立了一个工作组,以制定管理抗血小板或抗凝的骨质疏松性髋部骨折患者的行动计划。所建议的建议基于最佳实践的证据,并已由6个专业组成的多学科小组验证。

结果

早期手术可减少并发症和死亡率,并改善患者舒适度和功能恢复,硬膜内麻醉和全身麻醉的死亡率无差异。

结论

尽管仍存在不确定性,但建议在入院后24 - 48小时内进行手术,根据止血情况调整周围神经阻滞和麻醉类型(椎管内或全身)。建议自入院起对抗血栓药物进行多模式管理,并优化止血、血红蛋白和静脉血栓预防。

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