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有压迫症状的椎体血管瘤的手术疗效:一项机构经验

Surgical Outcomes for Vertebral Body Hemangiomas With Compressive Symptoms: An Institutional Experience.

作者信息

Kanaujia Niraj, Kumar Brajesh, Gupta Om Prakash, Singh Samendra Kumar, Kumar Brajesh

机构信息

Neurosurgery, Indira Gandhi Institute of Medical Sciences, Patna, IND.

出版信息

Cureus. 2024 Nov 4;16(11):e73014. doi: 10.7759/cureus.73014. eCollection 2024 Nov.

Abstract

Background Vertebral hemangiomas (VHs) are benign vascular tumors commonly found within the vertebral bodies of the spine. While most VHs remain asymptomatic and are often discovered incidentally during imaging studies, a subset can become symptomatic, leading to clinical challenges. The optimal treatment approach for symptomatic VHs remains a topic of debate. At our institution, we have managed aggressive VHs through a combination of surgical decompression and intraoperative alcohol ablation. The objective of this research is to evaluate the effectiveness of a combined treatment approach involving intralesional ethanol injection, surgical decompression, and stabilization using titanium polyaxial screws and rods in managing symptomatic VHs with compressive symptoms. Methodology A prospective longitudinal study was conducted at the Indira Gandhi Institute of Medical Science, Patna, in patients with symptomatic VHs associated with compressive myelopathy. The operative plan involved bilateral transpedicular intralesional injection of absolute alcohol (<1% hydrated ethyl alcohol), followed by laminectomy decompression and stabilization of the affected segment using polyaxial titanium pedicle screws and rods. Results A total of 19 patients were included in the study, consisting of 10 females and nine males, all presenting with back pain, myelopathy, and sphincter dysfunction. Preoperative American Spinal Injury Association (ASIA) scores were as follows: A (9), B (5), C (3), D (2), and E (0). The average duration of the surgery was 120 minutes, with a standard deviation of 30 minutes. The average blood loss recorded was 250 cc, with a variability of 50 cc, and the typical volume of absolute alcohol utilized was 6 ml, with a standard deviation of 5 ml. Postoperatively, all patients showed improvement, with follow-up ASIA scores of E (9), D (5), B (3), and C (2). Conclusions The use of intraoperative ethanol as an embolizing agent, laminectomy decompression, and stabilization using screws and rods for symptomatic VHs seems to be ideal treatment modality in resource-poor countries like India.

摘要

背景

椎体血管瘤(VHs)是常见于脊柱椎体的良性血管肿瘤。虽然大多数VHs无症状,常在影像学检查时偶然发现,但有一部分会出现症状,带来临床挑战。有症状VHs的最佳治疗方法仍是一个有争议的话题。在我们机构,我们通过手术减压和术中酒精消融相结合的方法来处理侵袭性VHs。本研究的目的是评估一种联合治疗方法的有效性,该方法包括病灶内乙醇注射、手术减压以及使用钛多轴螺钉和棒进行固定,用于治疗有压迫症状的有症状VHs。

方法

在巴特那的英迪拉·甘地医学科学研究所对有症状VHs伴脊髓压迫症的患者进行了一项前瞻性纵向研究。手术方案包括双侧经椎弓根病灶内注射无水乙醇(<1%水合乙醇),随后行椎板切除术减压,并使用多轴钛椎弓根螺钉和棒对受累节段进行固定。

结果

本研究共纳入19例患者,其中女性10例,男性9例,均表现为背痛、脊髓病和括约肌功能障碍。术前美国脊髓损伤协会(ASIA)评分如下:A(9例)、B(5例)、C(3例)、D(2例)和E(0例)。手术平均时长为120分钟,标准差为30分钟。记录的平均失血量为2..cc,变异度为50 cc,使用的无水乙醇典型用量为6 ml,标准差为5 ml。术后,所有患者均有改善,随访时ASIA评分分别为E(9例)、D(5例)、B(3例)和C(2例)。

结论

在印度这样资源匮乏的国家,术中使用乙醇作为栓塞剂、椎板切除术减压以及使用螺钉和棒进行固定,对于有症状VHs似乎是理想的治疗方式。

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本文引用的文献

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[Vertebroplasty in the treatment of spinal diseases].[椎体成形术治疗脊柱疾病]
Zh Vopr Neirokhir Im N N Burdenko. 2004 Apr-Jun(2):21-5; discussion 26.

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