Deori Rupam, Neelakandan Diwakar, Algud Shivakumar M, Thomas Renu, Yadav Manish K, Vaidya Ajit N
Urology, Kerala Institute of Medical Sciences (KIMSHEALTH), Thiruvananthapuram, IND.
Interventional Radiology, Kerala Institute of Medical Sciences (KIMSHEALTH), Thiruvananthapuram, IND.
Cureus. 2024 Nov 5;16(11):e73064. doi: 10.7759/cureus.73064. eCollection 2024 Nov.
Introduction The purpose of this study is to assess the effectiveness and short-term outcomes of prostatic artery embolization (PAE) in Indian patients suffering from benign prostatic hyperplasia (BPH). Methods This retrospective analysis was performed at a single center and included 25 patients with BPH who received PAE from January 2019 to June 2023. The symptoms of patients had been assessed utilizing the International Prostate Symptom Score (IPSS) and the Quality of Life (QoL) questionnaire. The prostate volume and post-void residual (PVR) volume were assessed using transabdominal ultrasonography prior to and following the embolization. The procedure occurred in the interventional radiology suite with the patient under conscious anesthesia, employing polyvinyl alcohol (PVA) particles. Prostate volume, PVR, IPSS, and QoL scores had been assessed at a follow-up three months later. Results Twenty-five males, with an average age of 76.56 years, underwent PAE. Bilateral embolization was conducted in 23 patients, whereas unilateral embolization was executed in two cases. Following a duration of three months, the average maximum improvement was as defined: IPSS, 10.44 ± 2.91; QoL score, 1.80 ± 0.81; prostatic volume decrease, 49.40 ± 24.13 cc (43% ± 13.95); and PVR volume, 70.08 ± 39.85 mL (52% ± 14.14) (p < 0.001 for all) as evaluated by the paired t-test. Conclusion PAE is a secure and efficacious intervention for BPH, yielding favorable short-term outcomes for lower urinary tract symptoms.
引言 本研究的目的是评估前列腺动脉栓塞术(PAE)对患有良性前列腺增生(BPH)的印度患者的有效性和短期疗效。方法 本回顾性分析在单一中心进行,纳入了2019年1月至2023年6月期间接受PAE的25例BPH患者。利用国际前列腺症状评分(IPSS)和生活质量(QoL)问卷对患者的症状进行了评估。在栓塞前后使用经腹超声评估前列腺体积和残余尿量(PVR)。该手术在介入放射科进行,患者处于清醒麻醉状态,使用聚乙烯醇(PVA)颗粒。在三个月后的随访中评估了前列腺体积、PVR、IPSS和QoL评分。结果 25名男性接受了PAE,平均年龄为76.56岁。23例患者进行了双侧栓塞,2例进行了单侧栓塞。三个月后,平均最大改善情况如下:IPSS为10.44±2.91;QoL评分为1.80±0.81;前列腺体积减少49.40±24.13 cc(43%±13.95);PVR体积为70.08±39.85 mL(52%±14.14)(配对t检验评估,所有p值均<0.001)。结论 PAE是一种安全有效的BPH干预措施,对下尿路症状有良好的短期疗效。