Kumbhar Pragati Ramesh, Desai Harita, Desai Vaibhavi Meghraj, Priya Sakshi, Rana Vikas, Singhvi Gautam
Industrial Research Laboratory, Department of Pharmacy, Birla Institute of Technology and Science, Pilani (BITS-PILANI), Pilani, India.
Department of Pharmaceutics, Bombay College of Pharmacy, Mathuradas Colony, Mumbai, India.
Expert Opin Drug Deliv. 2025 Jan;22(1):55-68. doi: 10.1080/17425247.2024.2439457. Epub 2024 Dec 11.
Emulgel is a novel formulation that improves drug's stability and topical administration by combining emulsion and gel matrix. Its special structure improves skin penetration and prolongs the release of therapeutic molecules. Emulgel is unique in the commercial market because of its therapeutic effects, convenience of usage, and versatility in both pharmaceutical and cosmetic uses. This report focuses on how it may improve user experience and transform topical treatments.
This review explores the commercial applicability of emulgels as a topical delivery system. Industrially applicable composition and manufacturing strategies have been discussed along with characterization techniques. The market landscape, being the most critical aspect, has been thoroughly discussed with recent case studies, clinical trials, patents, and commercial formulations. The compiled findings in this review are adapted from reputed databases like Scopus, PubMed, Web of Science, NIH, ClinicalTrials.gov, Espacenet, and recent research articles published between years 2010-2024 that discussed the applications of emulgel.
Emulgels have gained commercialization potential because of their efficient drug delivery and patient-friendly qualities. However, navigating regulatory complexity is important because imprecise classifications may affect market access. Sustained innovation will be essential for overcoming these obstacles and improving chances in future.
乳胶凝胶是一种新型制剂,它通过将乳液和凝胶基质相结合来提高药物的稳定性和局部给药效果。其特殊结构可改善皮肤渗透并延长治疗分子的释放。乳胶凝胶因其治疗效果、使用便利性以及在制药和化妆品用途方面的多功能性而在商业市场中独树一帜。本报告重点关注它如何改善用户体验并变革局部治疗方法。
本综述探讨了乳胶凝胶作为局部给药系统的商业适用性。已讨论了工业适用的成分和制造策略以及表征技术。作为最关键的方面,市场格局已通过近期案例研究、临床试验、专利和商业制剂进行了深入讨论。本综述中汇编的研究结果改编自Scopus数据库、PubMed数据库、科学网、美国国立医学图书馆、ClinicalTrials.gov、欧洲专利局等知名数据库以及2010年至2024年间发表的讨论乳胶凝胶应用的近期研究文章。
乳胶凝胶因其高效的药物递送和对患者友好的特性而具有商业化潜力。然而,应对监管复杂性很重要,因为不精确的分类可能会影响市场准入。持续创新对于克服这些障碍并提高未来的机遇至关重要。