Martín-Núñez Javier, de Castro Sheila Gómez, Heredia-Ciuró Alejandro, Navas-Otero Alba, Cabrera-Martos Irene, Ortiz-Rubio Araceli, Valenza Marie Carmen
From the Department of Physiotherapy, Faculty of Health Sciences, University of Granada, Granada, Spain.
Am J Phys Med Rehabil. 2025 Jul 1;104(7):605-612. doi: 10.1097/PHM.0000000000002676. Epub 2024 Dec 3.
This study was to examine the effects of high-intensity interval training interventions on exercise capacity and fatigue in people with multiple sclerosis.
We performed a systematic review and meta-analysis. PubMed/MEDLINE, Web of Science, Scopus, and Google Scholar databases were systematically searched from inception to January 2024. We reviewed randomized controlled trials that focused their intervention on high-intensity interval training for people with multiple sclerosis to improve exercise capacity or fatigue. Two researchers performed the search process independently in the different databases and assessed methodological quality and risk of bias.
Eleven studies were included in the systematic review and seven of them were meta-analyzed. The overall pooled effect favored high-intensity interval training interventions in improving exercise capacity (standardized mean difference = 0.29; 95% confidence interval = 0.05, 0.53; P = 0.02) and reducing fatigue (standardized mean difference = -0.26; 95% confidence interval = -0.50, -0.02; P = 0.03) in people with multiple sclerosis. We generally found a low risk of bias and a good methodological quality.
The results of this review and meta-analysis provide evidence that high-intensity interval training interventions improved and reduced fatigue in people with multiple sclerosis. High-intensity interval training intervention may be a good option to improve exercise capacity and reduce fatigue of these people.
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Upon completion of this article, the reader should be able to: (1) Determine the impact that whiplash-associated disorders have on a patient's life; (2) Identify and recognize the greater benefits of a supervised exercise therapy on recovery after a whiplash injury; and (3) Differentiate between the different exercise protocols conducted (types of exercises and duration) and incorporate therapy appropriately as part of an effective treatment plan.
Advanced.
The Association of Academic Physiatrists is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.The Association of Academic Physiatrists designates this Journal-based CME activity for a maximum of 1.0 AMA PRA Category 1 Credit(s) ™. Physicians should only claim credit commensurate with the extent of their participation in the activity.
本研究旨在探讨高强度间歇训练干预对多发性硬化症患者运动能力和疲劳的影响。
我们进行了一项系统评价和荟萃分析。从数据库创建至2024年1月，对PubMed/MEDLINE、Web of Science、Scopus和谷歌学术数据库进行了系统检索。我们纳入了将干预重点放在对多发性硬化症患者进行高强度间歇训练以提高运动能力或减轻疲劳的随机对照试验。两名研究人员在不同数据库中独立进行检索过程，并评估方法学质量和偏倚风险。
系统评价纳入了11项研究，其中7项进行了荟萃分析。总体合并效应表明，高强度间歇训练干预有利于改善多发性硬化症患者的运动能力（标准化均数差=0.29；95%置信区间=0.05，0.53；P=0.02）和减轻疲劳（标准化均数差=-0.26；95%置信区间=-0.50，-0.02；P=0.03）。我们总体上发现偏倚风险较低且方法学质量良好。
本综述和荟萃分析的结果提供了证据，表明高强度间歇训练干预可改善多发性硬化症患者的运动能力并减轻疲劳。高强度间歇训练干预可能是提高这些患者运动能力和减轻疲劳的一个良好选择。
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阅读本文后，读者应能够：（1）确定挥鞭样损伤相关疾病对患者生活的影响；（2）识别并认识到有监督的运动疗法对挥鞭样损伤后恢复的更大益处；（3）区分所采用的不同运动方案（运动类型和持续时间），并将治疗作为有效治疗计划的一部分进行适当整合。
高级。
学术物理医学与康复医师协会经继续医学教育认证委员会认可，可为医生提供继续医学教育。学术物理医学与康复医师协会将此基于期刊的继续医学教育活动指定为最多1.0个美国医学协会医师认可奖第1类学分™。医生应仅根据其参与活动的程度索取学分。
