Kahn Laureline, Poillon Guillaume, Elmaleh-Bergès Monique, Litman-Roventa Luca, Chebib Emilien, Teissier Natacha, Maudoux Audrey
Department of Paediatric Otolaryngology, Robert Debre Hospital, Assistance Publique Hôpitaux de Paris (APHP), Paris Cité University, Paris, France.
Fondation Adolphe-de-Rothschild Hospital, Paris, France.
Int J Pediatr Otorhinolaryngol. 2025 Jan;188:112172. doi: 10.1016/j.ijporl.2024.112172. Epub 2024 Nov 19.
To describe the inner ear sectors after an inner ear MRI protocol and search for the presence of endolymphatic pressure anomaly in patients presenting with a congenital CMV infection and audio-vestibular dysfunction.
A 3D FLAIR MRI sequence, 4 h after gadolinium injection, was performed in patients with sensory-neural hearing loss secondary to a congenital CMV infection in order to analyse the morphology of the endolymphatic space.
Two patients presented with a unilateral SNHL and 4 patients a bilateral SNHL. Seven ears with SNHL demonstrated an endolymphatic hydrops on MRI images and 2 showed a membranous labyrinth atelectasis. All ears but two had a marked enhancement in the perilymph of the basal turn of the cochlea. One ear, with a normal hearing threshold but altered vestibular function, demonstrated cochlear and saccular hydrops. Two ears with normal or near normal hearing and normal vestibular function were radiologically normal on the MRI.
The compartmental endolymphatic study using delayed contrast-enhanced MRI sequences in children with cCMV infection suggests a relationship between inner ear involvement and endolymphatic pressure anomaly.
描述内耳MRI检查后的内耳区域，并在先天性巨细胞病毒（CMV）感染及听觉-前庭功能障碍患者中寻找内淋巴压力异常的存在情况。
对先天性CMV感染继发感音神经性听力损失的患者，在注射钆剂4小时后进行三维液体衰减反转恢复（FLAIR）MRI序列检查，以分析内淋巴间隙的形态。
2例患者表现为单侧感音神经性听力损失（SNHL），4例为双侧SNHL。7只存在SNHL的耳朵在MRI图像上显示有内淋巴积水，2只显示膜迷路萎陷。除2只耳朵外，其余所有耳朵的耳蜗基底转外淋巴均有明显强化。1只听力阈值正常但前庭功能异常的耳朵显示有耳蜗和球囊积水。2只听力正常或接近正常且前庭功能正常的耳朵在MRI上影像学表现正常。
在先天性CMV感染儿童中使用延迟对比增强MRI序列进行内淋巴分区研究表明，内耳受累与内淋巴压力异常之间存在关联。
