通用的Rhs壳结构在内部容纳各种毒素，在外部有不同的功能修饰。

The universal Rhs shell structure accommodates various toxins inside and different functional decorations on the outside.

作者信息

Jurėnas Dukas

机构信息

Bacterial Genetics and Physiology, Faculté des Sciences, Université Libre de Bruxelles (ULB), Gosselies, Belgium; WEL Research Institute, avenue Pasteur 6, 1300 Wavre, Belgium.

出版信息

Structure. 2024 Dec 5;32(12):2185-2187. doi: 10.1016/j.str.2024.11.003.

DOI:10.1016/j.str.2024.11.003

PMID:39642849

Abstract

In this issue of Structure, Kielkopf et al. report the crystal structures of Rhs proteins that are genetically fused to the type VI secretion system PAAR or VgrG proteins. The work highlights the structural similarities of Rhs proteins despite diverse decorations surrounding the Rhs core and different delivery modes.

摘要

在本期《结构》杂志中，基尔科夫等人报道了与VI型分泌系统PAAR或VgrG蛋白基因融合的Rhs蛋白的晶体结构。这项工作突出了Rhs蛋白的结构相似性，尽管Rhs核心周围有不同的修饰以及不同的递送模式。