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2003年至2022年科索沃和梅托希亚塞尔维亚社区全国儿童免疫规划覆盖率趋势:新冠疫情前时期与新冠疫情期间

The trend in national childhood immunization program coverage throughout Serbian communities in Kosovo and Metohija from 2003 to 2022: pre-COVID-19 period vs. COVID-19 pandemic.

作者信息

Filimonovic Jelena, Stosic Maja, Gazibara Tatjana, Dotlic Jelena, Joksimovic Bojan, Subaric Aleksandar, Stevanovic Jasmina, Radulovic Aleksandra, Mijovic Biljana, Subaric Ljiljana, Kovacevic Milica, Radulovic Jana, Antonijevic Aleksandar, Milic Marija

机构信息

Department of Epidemiology, Faculty of Medicine, University of Pristina temporarily settled in Kosovska Mitrovica, Kosovska Mitrovica, Serbia; Public Health Institute of Kosovska Mitrovica, Kosovska Mitrovica, Serbia.

Faculty for Health and Business Studies, Singidunum University, Valjevo, Serbia.

出版信息

Vaccine. 2025 Jan 12;44:126576. doi: 10.1016/j.vaccine.2024.126576. Epub 2024 Dec 5.

Abstract

BACKGROUND

The childhood immunization coverage in Serbian communities in Kosovo after the 1999 armed conflict has not been investigated. The study purpose was to evaluate the trend of immunization coverage with vaccines from the national childhood immunization program in Serbian communities in Kosovo and Metohija from 2003 to 2022.

METHODS

Data were retrieved from the annual reports of the Public Health Institute of Kosovska Mitrovica received through notifications from the primary health centers where vaccines are being administered. Data were analyzed using the linear regression and join-point regression models.

RESULTS

In the examined period, a significant decrease in vaccination coverage was observed for the following diseases: diphtheria, tetanus and pertussis (DTP), polio, as well as measles, mumps and rubella vaccines (MMR), then, the first revaccination for DTP and polio, the second revaccination against diphtheria and tetanus for children (DT) and polio, and the third revaccination against diphtheria and tetanus for adults (dT), as well as the second dose of the MMR vaccine. During the COVID-19 pandemic, a significant decrease in coverage was observed for primary vaccination against: DTP, polio and hepatitis B, first and second doses of the MMR vaccine, as well as the first and second revaccination for DTP and polio, and the third revaccination for dT.

CONCLUSION

A decline in coverage with DTP, MMR, polio and hepatitis B vaccines was observed between 2003 and 2022. This was even more pronounced during the COVID-19 pandemic. Further research on individual-level factors contributing to lower vaccination coverage is warranted.

摘要

背景

1999年武装冲突后,科索沃塞尔维亚族社区的儿童免疫接种覆盖率尚未得到调查。本研究的目的是评估2003年至2022年科索沃和梅托希亚塞尔维亚族社区国家儿童免疫规划疫苗的免疫接种覆盖率趋势。

方法

数据取自科索沃米特罗维察公共卫生研究所的年度报告,这些报告通过正在进行疫苗接种的初级卫生中心的通知获得。使用线性回归和连接点回归模型对数据进行分析。

结果

在研究期间,观察到以下疾病的疫苗接种覆盖率显著下降:白喉、破伤风和百日咳(DTP)、脊髓灰质炎,以及麻疹、腮腺炎和风疹疫苗(MMR),然后是DTP和脊髓灰质炎的首次复种、儿童白喉和破伤风(DT)及脊髓灰质炎的第二次复种、成人白喉和破伤风(dT)的第三次复种,以及MMR疫苗的第二剂。在新冠疫情期间,观察到以下疫苗的初次接种覆盖率显著下降:DTP、脊髓灰质炎和乙肝疫苗、MMR疫苗的第一剂和第二剂,以及DTP和脊髓灰质炎的首次和第二次复种、dT的第三次复种。

结论

2003年至2022年期间,观察到DTP、MMR、脊髓灰质炎和乙肝疫苗的接种覆盖率下降。在新冠疫情期间,这种情况更为明显。有必要进一步研究导致疫苗接种覆盖率较低的个体层面因素。

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