心脏髓系肉瘤——临床病理相关性

Myeloid sarcoma of the heart-A clinicopathological correlation.

作者信息

Skok Kristijan, Zacharias Martin, Verheyen Nicolas, Hatzl Stefan, Scholz Laura, Langner Cord, Hoefler Gerald, Vagena Fotini Rosi

机构信息

Diagnostic and Research Institute of Pathology, Medical University of Graz, Stiftingtalstraße 6, 8010, Graz, Austria.

Division of Cardiology, Department of Internal Medicine, Medical University of Graz, Medical University of Graz, Auenbruggerplatz 15, 8036, Graz, Austria.

出版信息

Wien Klin Wochenschr. 2025 Apr;137(7-8):251-254. doi: 10.1007/s00508-024-02478-3. Epub 2024 Dec 6.

DOI:10.1007/s00508-024-02478-3

PMID:39643753

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12006259/

Abstract

A 63-year-old woman with a history of acute myeloid leukemia followed by stem cell transplantation presented with acute heart failure. Transthoracic echocardiography revealed a preserved left ventricular ejection fraction with severe ventricular hypertrophy and signs of elevated filling pressures indicating infiltrative cardiomyopathy. She died from cardiac arrest due to cardiogenic shock. The autopsy revealed an enlarged heart with a fish-flesh appearance. Here, we describe a rare case of a myeloid sarcoma of the heart.

摘要

一名63岁女性，有急性髓系白血病病史，之后接受了干细胞移植，现出现急性心力衰竭。经胸超声心动图显示左心室射血分数正常，但有严重的心室肥厚以及充盈压升高的迹象，提示浸润性心肌病。她因心源性休克导致心脏骤停死亡。尸检发现心脏增大，外观呈鱼肉样。在此，我们描述一例罕见的心脏髓系肉瘤病例。