Collin J R, Allen L H, Garner A, Hungerford J L
Aust N Z J Ophthalmol. 1986 Feb;14(1):29-34. doi: 10.1111/j.1442-9071.1986.tb00004.x.
Four patients with malignant melanoma of the eyelid skin and 14 patients with conjunctival malignant melanoma are presented. Surgery was recommended for eyelid lesions and local excision followed by cryotherapy for conjunctival lesions. One patient with an eyelid skin malignant melanoma died and two patients with extensive malignant melanoma of the conjunctiva died. Nodular lesions involving the lid margin have the worst prognosis of eyelid skin malignant melanomas, and the greater the extent of conjunctival involvement the worse the prognosis for conjunctival malignant melanomas. The complications of cryotherapy are minor, but the follow-up period in this series is too short to comment on survival times.
本文报告了4例眼睑皮肤恶性黑色素瘤患者和14例结膜恶性黑色素瘤患者。对于眼睑病变建议手术治疗,结膜病变则采用局部切除后冷冻治疗。1例眼睑皮肤恶性黑色素瘤患者死亡,2例结膜广泛恶性黑色素瘤患者死亡。累及睑缘的结节性病变是眼睑皮肤恶性黑色素瘤中预后最差的,结膜受累范围越大,结膜恶性黑色素瘤的预后越差。冷冻治疗的并发症轻微,但本系列的随访期太短,无法对生存时间作出评价。