Dijxhoorn M J, Visser G H, Fidler V J, Touwen B C, Huisjes H J
Br J Obstet Gynaecol. 1986 Mar;93(3):217-22. doi: 10.1111/j.1471-0528.1986.tb07896.x.
The relation between Apgar score, meconium and acidaemia at birth and neonatal neurological morbidity was investigated in 805 vaginally born term infants whose birthweight was appropriate-for-dates (AFD). Presence or absence of meconium stained amniotic fluid was not related to the neonatal neurological condition. The 1-min and 3-min Apgar scores and the umbilical artery pH were related, but the variances explained in neonatal neurological optimality score were very low (0.9 and 0.5% respectively). Combination of Apgar score and pH slightly increased these percentages to 1.5. The highest frequency of neurologically deviant infants was, on the other hand, found in the group with a normal pH but low Apgar score. It is concluded that in AFD term infants nowadays the predictive value of a low Apgar score, acidaemia at birth and/or presence of meconium for the neonatal neurological morbidity is poor. Most neonatal neurological abnormalities must be due to other factors.
对805名出生体重与孕周相符的足月阴道分娩婴儿进行了研究，以探讨出生时阿氏评分、胎粪及酸血症与新生儿神经疾病发生率之间的关系。羊水是否被胎粪污染与新生儿神经状况无关。1分钟和3分钟阿氏评分与脐动脉pH值相关，但它们对新生儿神经最佳评分的解释方差非常低（分别为0.9%和0.5%）。阿氏评分和pH值相结合可将这些百分比略微提高至1.5%。另一方面，神经功能异常婴儿的最高发生率出现在pH值正常但阿氏评分低的组中。得出的结论是，如今对于出生体重与孕周相符的足月婴儿，低阿氏评分、出生时酸血症和/或胎粪的存在对新生儿神经疾病发生率的预测价值较差。大多数新生儿神经异常必定归因于其他因素。
