Dijxhoorn M J, Visser G H, Touwen B C, Huisjes H J
Department of Obstetrics and Gynaecology, University Hospital Groningen, The Netherlands.
Br J Obstet Gynaecol. 1987 Sep;94(9):873-9. doi: 10.1111/j.1471-0528.1987.tb03758.x.
Neonatal neurological morbidity was studied in relation to Apgar score, meconium stained amniotic fluid and acidaemia at birth in 247 small-for-gestational age (SGA) maturely born infants. SGA infants, and especially the severely SGA infants and those born abdominally, showed higher rates of neurological morbidity, acidaemia and meconium stained amniotic fluid than appropriate-for-gestational age (AGA) controls. The examined indicators of asphyxia at birth showed slightly higher correlation coefficients with the 'neonatal neurological optimality score' (NNOS) in SGA, than in AGA term infants, but the percentage of explained variance was low, except in the 23 infants born abdominally. In this group poor neurological outcome was restricted to the 14 infants who showed signs of fetal hypoxaemia diagnosed by decelerative fetal heart rate (FHR) patterns. In 11 of them, FHR decelerations occurred antepartum. These FHR abnormalities appear to be better predictors for the neonatal neurological outcome than indicators of asphyxia at birth.
对247例足月出生的小于胎龄（SGA）婴儿的新生儿神经疾病发病率与阿氏评分、胎粪污染羊水及出生时酸血症的关系进行了研究。SGA婴儿，尤其是严重SGA婴儿和经腹出生的婴儿，其神经疾病发病率、酸血症及胎粪污染羊水的发生率高于适于胎龄（AGA）的对照婴儿。所检测的出生时窒息指标与SGA婴儿的“新生儿神经最优评分”（NNOS）的相关系数略高于AGA足月儿，但除经腹出生的23例婴儿外，可解释变异的百分比很低。在这组婴儿中，神经结局不良仅限于14例通过胎儿心率减速（FHR）模式诊断出有胎儿低氧血症迹象的婴儿。其中11例，FHR减速发生在产前。这些FHR异常似乎比出生时窒息指标更能预测新生儿神经结局。
