与特定男性不育症和隐匿性女性不育症相关的供体人工授精结果。

Results of donor insemination related to specific male infertility and unsuspected female infertility.

作者信息

Foss G L, Hull M G

出版信息

Br J Obstet Gynaecol. 1986 Mar;93(3):275-8. doi: 10.1111/j.1471-0528.1986.tb07907.x.

DOI:10.1111/j.1471-0528.1986.tb07907.x

Abstract

Apparently normal but infertile women were treated by artificial insemination using fresh donor semen. In 228 couples in which the male partner was azoospermic the average monthly conception rate was 13.3% and the 12-month cumulative rate was 82.2% (SE 2.7%). In 116 couples in which the partner was oligospermic the monthly rate was 8.7% and the 12-month rate 66.6% (SE 5.0%, P less than 0.01). Previous smaller studies have given rise to conflicting or inconclusive results, but the reduced conception rates in the partners of oligospermic men in this large study suggests that unexplained female factors, discussed in the paper, contribute to their infertility in up to a third of patients.

摘要

表面上正常但不孕的女性接受了使用新鲜供体精液的人工授精治疗。在228对男性伴侣无精子症的夫妇中，平均每月受孕率为13.3%，12个月累积受孕率为82.2%（标准误2.7%）。在116对伴侣为少精子症的夫妇中，每月受孕率为8.7%，12个月受孕率为66.6%（标准误5.0%，P<0.01）。之前规模较小的研究得出了相互矛盾或不确定的结果，但在这项大型研究中，少精子症男性伴侣受孕率降低表明，本文讨论的不明原因女性因素在多达三分之一的患者中导致了他们的不孕。