Pregnancy rates with artificial insemination by donor: the influence of the cryopreservation method and coexistent infertility factors.

Women entering the AID programme in Dunedin since 1983 were studied to assess the clinical performance of cryopreservation modifications as well as the early assessment of coexistent infertility factors. The cumulative pregnancy rate for normal pregnancies was 45.5% and 64.7% for three months and six months respectively. The conception rate per cycle was 17.9%. These compare favourably with the use of fresh semen in other reports. Except for endometriosis and possibly tubal polyps, treatment of coexistent infertility factors retained this conception rate. With refinements in techniques it is possible that conception rates with AID could approach those of normal fertility.