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到2040年澳大利亚成年人和儿童中关节炎的预计负担:一项基于人群水平的预测研究。

The projected burden of arthritis among adults and children in Australia to the year 2040: a population-level forecasting study.

作者信息

Ackerman Ilana N, Gorelik Alexandra, Berkovic Danielle, Buchbinder Rachelle

机构信息

Musculoskeletal Health and Wiser Health Care Units, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.

Musculoskeletal Health and Wiser Health Care Units, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; Department of Medicine, Royal Melbourne Hospital, The University of Melbourne, Melbourne, VIC, Australia.

出版信息

Lancet Rheumatol. 2025 Mar;7(3):e187-e196. doi: 10.1016/S2665-9913(24)00247-9. Epub 2024 Dec 5.

Abstract

BACKGROUND

Understanding how many people could be living with arthritis in the future is essential for planning health service needs and national health workforce requirements, and for arthritis advocacy and policy development. This study aimed to forecast the size of different populations with arthritis in Australia and associated health system expenditure, up to the year 2040.

METHODS

In this population-level forecasting study for Australia, prevalence data for arthritis, osteoarthritis, and rheumatoid arthritis were obtained from the Australian Bureau of Statistics 2022 National Health Survey. Prevalence rates for juvenile idiopathic arthritis were sourced from 2021 Census data. Overall, age-specific and sex-specific prevalence data were applied to national population projections to forecast arthritis, osteoarthritis, rheumatoid arthritis, and juvenile idiopathic arthritis populations for 2025, 2030, 2035, and 2040. The base case analysis considered medium population growth; sensitivity analyses considered low and high growth scenarios. Health system expenditure data from the Australian Institute of Health and Welfare were extrapolated to base case projections for the years 2025, 2030, 2035, and 2040, and were then inflated to future dollars. To understand the broader context and implications of our projections through the lens of lived experience, an arthritis consumer researcher and members of the Arthritis Australia Consumer Advisory Panel reviewed the arthritis burden estimates.

FINDINGS

With population growth and ageing, 5·39 million (95% CI 5·19-5·58) people are projected to have arthritis in Australia in 2040, representing an increase of 31% from 4·11 million (3·95-4·27) in 2025. By 2040, 3·11 million (2·99-3·23) people are expected to have osteoarthritis, 749 000 (652 000-846 000) are expected to have rheumatoid arthritis, and about 8500 children and adolescents are expected to have juvenile idiopathic arthritis. The age-standardised rate of osteoarthritis is forecast to increase for males from 6·28% in 2025 to 7·03% in 2040, and for females from 10·82% to 12·18% over this period. The age-standardised rate of rheumatoid arthritis is forecast to increase for males from 1·56% in 2025 to 1·75% in 2040, and for females from 2·62% in 2025 to 2·94% in 2040. Little change is anticipated in the number of children and adolescents with juvenile idiopathic arthritis (estimated at 8500 individuals in 2040). Based on current spending levels of AU$2100 per person with osteoarthritis and $1918 per person with rheumatoid arthritis, annual health system expenditure for osteoarthritis and rheumatoid arthritis is conservatively forecast to exceed AU$11·92 billion by 2040.

INTERPRETATION

Using the latest national-level data, this study has generated contemporary projections of the substantial burden of arthritis (both population size and health-care costs) in Australia. These projections underscore the importance of well-resourced health services that can capably deliver timely, high-value care to a growing number of people with arthritis.

FUNDING

Arthritis Australia and National Health and Medical Research Council.

摘要

背景

了解未来可能患有关节炎的人数对于规划卫生服务需求和国家卫生人力需求,以及开展关节炎宣传和政策制定至关重要。本研究旨在预测到2040年澳大利亚不同关节炎患者群体的规模以及相关卫生系统支出。

方法

在这项针对澳大利亚的人群水平预测研究中,关节炎、骨关节炎和类风湿关节炎的患病率数据来自澳大利亚统计局2022年全国健康调查。青少年特发性关节炎的患病率数据来自2021年人口普查数据。总体而言,将特定年龄和性别的患病率数据应用于全国人口预测,以预测2025年、2030年、2035年和2040年的关节炎、骨关节炎、类风湿关节炎和青少年特发性关节炎患者人数。基础病例分析考虑中等人口增长;敏感性分析考虑低增长和高增长情景。将澳大利亚卫生与福利研究所的卫生系统支出数据外推至2025年、2030年、2035年和2040年的基础病例预测,然后折算为未来货币价值。为了从生活经验的角度理解我们预测的更广泛背景和影响,一位关节炎消费者研究人员和澳大利亚关节炎消费者咨询小组的成员审查了关节炎负担估计数。

结果

随着人口增长和老龄化,预计到2040年澳大利亚将有539万人(95%置信区间519 - 558万)患有关节炎,比2025年的411万人(395 - 427万)增加31%。到2040年,预计将有311万人(299 - 323万)患有骨关节炎,74.9万人(65.2 - 84.6万)患有类风湿关节炎,约8500名儿童和青少年患有青少年特发性关节炎。预计在此期间,男性骨关节炎的年龄标准化患病率将从2025年的6.28%升至2040年的7.03%,女性从10.82%升至1第十二条18%。预计青少年特发性关节炎患儿和青少年人数变化不大(预计2040年为8500人)。根据目前每人患骨关节炎支出2100澳元、患类风湿关节炎支出1918澳元的水平,保守估计到204第十条骨关节炎和类风湿关节炎的年度卫生系统支出将超过119.2亿澳元。

解读

本研究利用最新的国家级数据,对澳大利亚关节炎的巨大负担(包括患者人数和医疗费用)进行了当代预测。这些预测强调了资源充足的卫生服务的重要性,这些服务能够为越来越多的关节炎患者提供及时、高价值的护理。

资金来源

澳大利亚关节炎协会和国家卫生与医学研究委员会。

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