一项评估经皮穴位电刺激对脑血管意外手术后患者胃肠动力、营养状况及免疫功能影响的随机对照试验。
A Randomized Controlled Trial Assessing the Impact of Transcutaneous Electrical Acupoint Stimulation on Gastrointestinal Motility, Nutritional Status, and Immune Function in Patients Following Cerebrovascular Accident Surgery.
作者信息
Chen Yuequn, A Shixin, Liu Cheng, Zhang Tao, Yang Jintao, Tian Xin
机构信息
Department of Intensive Care Unit, Fifth Affiliated Hospital of Wenzhou Medical University, Lishui Municipal Central Hospital, Lishui, China.
Department of Internal Medicine, Wenzhou Medical University, Wenzhou, China.
出版信息
J Invest Surg. 2024 Dec;37(1):2434093. doi: 10.1080/08941939.2024.2434093. Epub 2024 Dec 8.
BACKGROUND
Transcutaneous Electrical Acupoint Stimulation (TEAS) is a technique that involves stimulating specific acupoints on the body with electrical currents. It may regulate nerve excitability and improve nerve function. This study aimed to assess the impact of TEAS on gastrointestinal motility, nutrition, and immune function in patients post cerebrovascular accident surgery in the intensive care unit (ICU).
METHODS
A randomized controlled trial included 300 post-cerebrovascular surgery patients at Lishui Central Hospital (January 2021-June 2023). Patients were randomly assigned to TEAS or control groups in a 1:1 ratio. The TEAS group received TEAS at bilateral Zusanli (ST36), Shangjuxu (ST37), Tianshu (ST25), Neiguan (PC6), and Hegu (LI4) according to the International Acupuncture Point Code, plus standard care. The control group received routine enteral nutrition and sham TEAS. Nutritional, immune, and gastrointestinal motility indicators were compared.
RESULTS
A randomized controlled trial involving 300 post-surgery patients compared TEAS to sham TEAS, demonstrating significant enhancements ( < 0.05) in immune function and gastrointestinal motility. Compared to the control group, the TEAS group showed significant improvements in the patient's serum nutritional levels (prealbumin, albumin, hemoglobin, and total protein), immune status (IgG, IgA, IgM, and CD4+/CD8+), gastrointestinal motility (daily gastric residual volume, time to achieve target feeding volume, time for nutritional fluid to meet standards, time to first bowel movement, time to first passage of activated charcoal stool, time to reach the defecation volume), and overall condition (the scores of clinical scales and ICU stay duration) ( < 0.05). The TEAS group also experienced a significantly lower incidence of adverse events ( < 0.05).
CONCLUSIONS
Early TEAS intervention positively impacted recovery, shortened ICU stay, and improved outcomes in patients post cerebrovascular accident surgery.
背景
经皮穴位电刺激（TEAS）是一种通过电流刺激身体特定穴位的技术。它可能调节神经兴奋性并改善神经功能。本研究旨在评估TEAS对重症监护病房（ICU）脑血管意外手术后患者胃肠动力、营养和免疫功能的影响。
方法
一项随机对照试验纳入了丽水市中心医院300例脑血管意外手术后患者（2021年1月至2023年6月）。患者按1:1比例随机分为TEAS组或对照组。TEAS组根据国际穴位编码在双侧足三里（ST36）、上巨虚（ST37）、天枢（ST25）、内关（PC6）和合谷（LI4）接受TEAS治疗，并给予标准护理。对照组接受常规肠内营养和假TEAS治疗。比较营养、免疫和胃肠动力指标。
结果
一项涉及300例术后患者的随机对照试验将TEAS与假TEAS进行了比较，结果显示免疫功能和胃肠动力有显著增强（P<0.05）。与对照组相比，TEAS组患者的血清营养水平（前白蛋白、白蛋白、血红蛋白和总蛋白）、免疫状态（IgG、IgA、IgM和CD4+/CD8+）、胃肠动力（每日胃残余量、达到目标喂养量的时间、营养液达到标准的时间、首次排便时间、首次排出活性炭样便的时间、达到排便量的时间）以及总体状况（临床量表评分和ICU住院时间）均有显著改善（P<0.05）。TEAS组不良事件发生率也显著较低（P<0.05）。
结论
早期TEAS干预对脑血管意外手术后患者的康复有积极影响，缩短了ICU住院时间并改善了预后。
Zotero 插件