Wang M Y, Liu C, Zhang Y, Chen Y, Wu Q
Department of Ophthalmology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai200233, China.
Zhonghua Yan Ke Za Zhi. 2024 Dec 11;60(12):977-984. doi: 10.3760/cma.j.cn112142-20240508-00211.
To explore the corrective effect of cataract extraction surgery combined with a 2.8 mm steep-axis corneal incision under ophthalmic surgical navigation on low-to-moderate corneal astigmatism and different types of corneal astigmatism. A prospective cohort study was conducted. Patients with age-related cataract who underwent cataract extraction combined with single-focus intraocular lens implantation in the Department of Ophthalmology at the Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine from June to October 2023 and had a total corneal regular astigmatism degree of ≥0.50 D and <1.50 D were continuously collected. Patients were divided into a low-degree group (<1.00 D) and a moderate-degree group (≥1.00 D) according to corneal astigmatism degree. Simultaneously, they were classified into with-the-rule (WTR), against-the-rule (ATR), and oblique astigmatism based on preoperative corneal astigmatism axis position. Subjective refraction and anterior segment biometer examination were performed before and 3 months after surgery, respectively. Vector analysis of corneal astigmatism was conducted using the Alpins vector analysis method. The main observational indicators included target induced astigmatism, surgically induced astigmatism, and the correction index. A total of 95 patients (110 eyes) were collected in this study. Thirteen patients (18 eyes) were lost to follow-up, and finally 82 patients (92 eyes) were included. In the low-degree group, there were 14 males (16 eyes) and 26 females (23 eyes), with an age of (69.62±12.22) years. In the moderate-degree group, there were 13 males (15 eyes) and 33 females (35 eyes), with an age of (72.98±8.28) years. The target astigmatism correction amount, surgically induced astigmatism, and deviation vector in the low-degree group were all smaller than those in the moderate-degree group (all <0.05). Postoperative corneal astigmatism in both groups was undercorrected. The correction index in the low-degree group (0.88±0.44) was greater than that in the moderate-degree group (0.59±0.34) (=0.001), and the undercorrection proportion in the moderate-degree group (90.00%, 45/50) was much higher than that in the low-degree group (57.14%, 24/42). In the low-degree group, the correction index from high to low was WTR (1.07±0.41), oblique (0.90±0.58), and ATR astigmatism eyes (0.69±0.37). After multiple comparison analysis, the correction index of WTR astigmatism eyes was significantly higher than that of ATR astigmatism eyes (0.05). The success index from high to low was oblique (0.82±0.57), ATR (0.74±0.39), and WTR astigmatism eyes (0.68±0.43). In the moderate-degree group, the order of the correction index from high to low was the same as that in the low-degree group, also WTR (0.79±0.33), oblique (0.71±0.50), and ATR astigmatism eyes (0.53±0.30), but there was no statistical significance among the three (>0.05). In the low-degree group, there were 6 WTR astigmatism eyes undercorrected, fewer than 12 overcorrected eyes; there were 16 ATR astigmatism eyes undercorrected, more than 3 overcorrected eyes. In the moderate-degree group, there were 6 WTR astigmatism eyes undercorrected, more than 2 overcorrected eyes, but there were 2 ATR astigmatism eyes overcorrected, fewer than 34 undercorrected eyes. Cataract extraction surgery combined with a steep-axis corneal incision can achieve a certain astigmatism correction effect in patients with preoperative low-to-moderate corneal astigmatism. Patients with a preoperative corneal astigmatism degree of mild can achieve a better astigmatism correction effect than those with moderate, especially in the WTR astigmatism population. However, for cataract patients with preoperative corneal astigmatism of moderate and WTR astigmatism, a steep-axis corneal incision can also be combined to correct astigmatism as it can achieve the expected postoperative "with-the-rule undercorrection".
探讨眼科手术导航下白内障摘除手术联合2.8mm陡峭轴角膜切口对轻中度角膜散光及不同类型角膜散光的矫正效果。进行了一项前瞻性队列研究。连续收集2023年6月至10月在上海交通大学医学院附属第六人民医院眼科接受白内障摘除联合单焦点人工晶状体植入术、角膜总规则散光度数≥0.50D且<1.50D的年龄相关性白内障患者。根据角膜散光度数将患者分为低度组(<1.00D)和中度组(≥1.00D)。同时,根据术前角膜散光轴位将其分为顺规(WTR)、逆规(ATR)和斜向散光。分别在手术前和手术后3个月进行主观验光和眼前节生物测量仪检查。采用Alpins矢量分析法进行角膜散光的矢量分析。主要观察指标包括目标诱导散光、手术诱导散光和矫正指数。本研究共收集95例患者(110只眼)。13例患者(18只眼)失访,最终纳入82例患者(92只眼)。低度组中,男性14例(16只眼),女性26例(23只眼),年龄为(69.62±12.22)岁。中度组中,男性13例(15只眼),女性33例(35只眼),年龄为(72.98±8.28)岁。低度组的目标散光矫正量、手术诱导散光和偏差矢量均小于中度组(均<0.05)。两组术后角膜散光均欠矫。低度组的矫正指数(0.88±0.44)高于中度组(0.59±0.34)(P=0.001),中度组的欠矫比例(90.00%,45/50)远高于低度组(57.14%,24/42)。低度组中,矫正指数从高到低依次为WTR(1.07±0.41)、斜向(0.90±0.58)和ATR散光眼(0.69±0.37)。经多重比较分析,WTR散光眼的矫正指数显著高于ATR散光眼(P<0.05)。成功指数从高到低依次为斜向(0.82±0.57)、ATR(0.74±0.39)和WTR散光眼(0.68±0.43)。中度组中,矫正指数从高到低的顺序与低度组相同,也是WTR(0.79±0.33)、斜向(0.71±0.50)和ATR散光眼(0.53±0.30),但三者之间无统计学意义(P>0.05)。低度组中,有6只WTR散光眼欠矫,少于12只过矫眼;有16只ATR散光眼欠矫,多于3只过矫眼。中度组中,有6只WTR散光眼欠矫,多于2只过矫眼,但有2只ATR散光眼过矫,少于34只欠矫眼。白内障摘除手术联合陡峭轴角膜切口可在术前轻中度角膜散光患者中取得一定的散光矫正效果。术前角膜散光度数为轻度的患者比中度患者能获得更好的散光矫正效果,尤其是在WTR散光人群中。然而,对于术前角膜散光为中度且为WTR散光的白内障患者,也可联合陡峭轴角膜切口矫正散光,因为其可实现术后预期的“顺规欠矫”。