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胃癌腹腔镜胃切除术后胰瘘的危险因素及预防

Risk factors and prevention of pancreatic fistula after laparoscopic gastrectomy for gastric cancer.

作者信息

Liu Shan-Shan, Xie Hong-Yu, Chang Hao-Dong, Wang Liang, Yan Su

机构信息

Department of Gastrointestinal Oncology Surgery, The Affiliated Hospital of Qinghai University, Xining 810000, Qinghai Province, China.

出版信息

World J Gastrointest Surg. 2024 Nov 27;16(11):3413-3424. doi: 10.4240/wjgs.v16.i11.3413.

DOI:10.4240/wjgs.v16.i11.3413
PMID:39649189
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11622077/
Abstract

Following laparoscopic gastrectomy (LG), one of the critical complications that can arise is a pancreatic fistula (PF). The inability to promptly prevent, diagnose, and manage this condition can lead to severe complications and potentially be life-threatening for the patient. The incidence of PF post-LG in gastric cancer treatment is related to factors such as surgical approach, surgical instruments, characteristics of the pancreas itself, tumor stage, and the surgeon's experience. Currently, the diagnosis of postoperative PF is mainly based on the definition and diagnostic criteria consensus established by the International Study Group of Pancreatic Surgery. Gastrointestinal surgeons should be aware of the risk factors for PF, perform LG for gastric cancer with great care and precision, avoid pancreatic injury, and actively work to reduce the risk of postoperative PF.

摘要

腹腔镜胃切除术后(LG)可能出现的一种严重并发症是胰瘘(PF)。若不能及时预防、诊断和处理这种情况,可能会导致严重并发症,甚至对患者生命构成威胁。胃癌治疗中LG术后PF的发生率与手术方式、手术器械、胰腺本身特征、肿瘤分期以及外科医生的经验等因素有关。目前,术后PF的诊断主要基于国际胰腺手术研究组制定的定义和诊断标准共识。胃肠外科医生应了解PF的危险因素,谨慎、精确地进行胃癌的LG手术,避免胰腺损伤,并积极努力降低术后PF的风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b151/11622077/5e5ce42133ae/WJGS-16-3413-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b151/11622077/d77937ab9f9c/WJGS-16-3413-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b151/11622077/5e5ce42133ae/WJGS-16-3413-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b151/11622077/d77937ab9f9c/WJGS-16-3413-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b151/11622077/5e5ce42133ae/WJGS-16-3413-g002.jpg

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本文引用的文献

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Laparoscopic Versus Open Gastrectomy for Advanced Gastric Cancer: A Meta-Analysis of Randomized Controlled Trials.腹腔镜与开放胃切除术治疗进展期胃癌:一项随机对照试验的Meta分析
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Extended antibiotic therapy is associated with a lower rate of clinically relevant postoperative pancreatic fistula after pancreatoduodenectomy in intermediate- and high-risk patients: A single-institution analysis.
延长抗生素治疗与中高危患者胰十二指肠切除术后临床相关的术后胰瘘发生率降低相关:单中心分析。
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Indian J Cancer. 2023 Apr-Jun;60(2):152-159. doi: 10.4103/ijc.IJC_280_21.
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Pancreatic thickness as a predictor of postoperative pancreatic fistula after laparoscopic or robotic gastrectomy.腹腔镜或机器人胃切除术后胰腺厚度预测术后胰瘘。
Surg Endosc. 2023 Jul;37(7):5358-5367. doi: 10.1007/s00464-023-10021-0. Epub 2023 Mar 30.
6
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