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家畜颈动脉体的比较研究：形态学、生理学、组织学和病理学

Comparative exploration of the carotid body in domestic animals: morphology, physiology, histology, and pathology.

作者信息

Ecaterina Semzenisi, Hodor Dragos, Sall Ibrahima Mamadou, Toma Corina, Tăbăran Alexandru-Flaviu

机构信息

Department of Anatomic Pathology, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca, Romania.

出版信息

Front Vet Sci. 2024 Nov 22;11:1409701. doi: 10.3389/fvets.2024.1409701. eCollection 2024.

DOI:10.3389/fvets.2024.1409701
PMID:39649680
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11622254/
Abstract

The aim of the study was to present a review of the literature and research on the carotid body (CB) over the past years and update the latest findings. The purpose of this article is to present a general overview and comparative analysis of CB between species, from the microanatomy to the pathology of CB. This study gives information about the embryological development and physiological aspects of anatomical findings and their differences. The second part of the article gives a comparative analysis of the pathology of CB. Neoplasia of the CB in humans, namely, paraganglioma, in most cases, is part of a genetic MEN syndrome (multiple endocrine neoplasia). In dogs, paraganglioma is also involved with multiple neoplasia formations throughout the body, including endocrine and neuroendocrine glands. From this perspective, dogs are the most suitable specimens for studying carotid body tumors and their involvement in a MEN-like syndrome.

摘要

本研究的目的是对过去几年关于颈动脉体（CB）的文献和研究进行综述，并更新最新发现。本文的目的是对不同物种间的CB进行全面概述和比较分析，涵盖从CB的微观解剖到病理学。本研究提供了有关CB解剖学发现的胚胎发育和生理学方面及其差异的信息。文章的第二部分对CB的病理学进行了比较分析。人类CB的肿瘤形成，即副神经节瘤，在大多数情况下，是遗传性多发性内分泌肿瘤综合征（MEN）的一部分。在犬类中，副神经节瘤也与全身多处肿瘤形成有关，包括内分泌和神经内分泌腺体。从这个角度来看，犬类是研究颈动脉体肿瘤及其与类MEN综合征关系的最合适标本。

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