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10600纳米二氧化碳激光消融术治疗睑缘病变疗效的初步研究

A pilot study on the efficacy of 10600 nm carbon dioxide laser ablation in treatment of eyelid margin lesions.

作者信息

J P Prathibha, Bhingradia Yogesh M, Priya Devi, Pawar Smit B, Muthukumarasamy Vivek

机构信息

Department of Dermatology St Johns Medical College Hospital, Bangalore, Karnataka, India.

Department of Dermatology, Shivani Skin Care and Cosmetic Clinic, Surat, Gujarat, India.

出版信息

J Cutan Aesthet Surg. 2024 Oct-Dec;17(4):320-324. doi: 10.25259/jcas_145_23. Epub 2024 Sep 16.

Abstract

OBJECTIVES

Eyelid margin lesions cause discomfort by impeding both central and peripheral vision, depending on their position on the eyelids, thus hindering everyday routines. However, surgical excision, radiofrequency, electrocautery, and cryosurgery are employed for treatment, although they are complicated and have functional limitations. Carbon dioxide (CO) lasers were used to assess the efficacy, safety, and patient satisfaction with CO laser ablation in managing eyelid margin lesions.

MATERIAL AND METHODS

This is a pilot study of patients with eyelid margin lesions presented to a private clinic in urban Gujarat between June 2020 and June 2023. All patients were treated with a 10600 nm CO laser with a power of 1-2 W in continuous mode. The eyelid lesions were classified into three categories based on their size: Small (1-3 mm), medium (4-6 mm), and large (7-10 mm). The clinical response was assessed by the treating physician at week 1 and week 4, and categorized as excellent (complete clearance of lesion), moderate (>50%), or poor (<50%). Patients were asked to rate their level of satisfaction on a three-point scale at the end of the follow-up period: Dissatisfied, somewhat satisfied, or very satisfied.

RESULTS

Ten patients of all females with six of them having compound melanocytic nevi, two of them each had cystic hidradenoma, and one each had cyst of zeis and verruca vulgaris. Six of them had small lesions, two had medium, and two had large lesions. The clinical response grading of physicians at both 1 week and 4 weeks was excellent, and the patient satisfaction questionnaire yielded excellent outcomes.

CONCLUSION

The ablative CO laser is an excellent device used for the treatment of eyelid margin lesions, particularly when performed by an expert and skilled dermatologist. The application of this treatment approach has proven to be very beneficial and shows excellent results in terms of both the esthetic appearance and structural function of the eyelids.

摘要

目的

睑缘病变会阻碍中央和周边视力,根据其在眼睑上的位置导致不适,从而妨碍日常活动。然而,手术切除、射频、电灼和冷冻手术虽用于治疗,但操作复杂且存在功能限制。本研究使用二氧化碳(CO)激光评估CO激光消融治疗睑缘病变的疗效、安全性及患者满意度。

材料与方法

这是一项针对2020年6月至2023年6月期间就诊于古吉拉特邦城市一家私人诊所的睑缘病变患者的试点研究。所有患者均接受连续模式下功率为1 - 2W的10600nm CO激光治疗。睑缘病变根据大小分为三类:小(1 - 3mm)、中(4 - 6mm)和大(7 - 10mm)。治疗医生在第1周和第4周评估临床反应,并分为优(病变完全清除)、中(>50%)或差(<50%)。在随访期结束时,要求患者以三点量表对其满意度进行评分:不满意、有点满意或非常满意。

结果

所有患者均为女性,共10例,其中6例患有复合性黑素细胞痣,2例各患有囊性汗腺瘤,1例分别患有睑缘腺囊肿和寻常疣。其中6例为小病变,2例为中病变,2例为大病变。第1周和第4周医生的临床反应分级均为优,患者满意度调查问卷结果良好。

结论

消融性CO激光是治疗睑缘病变的一种优秀设备,尤其是由专业且技术熟练的皮肤科医生操作时。这种治疗方法的应用已被证明非常有益,在眼睑的美观外观和结构功能方面均显示出优异的效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fe9/11619172/bb4865d37fca/JCAS-17-320-g001.jpg

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