妊娠期急性有机磷中毒致早产：一例报告
Precipitate, preterm labor in acute organophosphate poisoning in pregnancy: a case report.
作者信息
Shah Rosy, Pokhrel Amrit, Shrestha Anil, Shrestha Saroj, Sah Amrita, Shah Raj
机构信息
Nepalgunj Medical College, Nepal.
Institute Of Medicine, Maharajgunj, Nepal.
出版信息
Ann Med Surg (Lond). 2024 Nov 14;86(12):7454-7457. doi: 10.1097/MS9.0000000000002721. eCollection 2024 Dec.
INTRODUCTION
Acute organophosphorus poisoning (AOPP) during pregnancy is uncommon. When complicated by preterm labor, it presents therapeutic dilemmas due to the lack of established guidelines.
CASE PRESENTATION
The authors describe a case of a 19-year-old primigravida at 33 weeks of gestation with AOPP. During her treatment, she unexpectedly experienced preterm, precipitate labor, resulting in the delivery of a live, healthy baby.
DISCUSSION
Late-pregnancy exposure to organophosphates may trigger preterm labor through receptor hyperstimulation from excess acetylcholine, causing premature contractions. Atropine, progesterone, and magnesium sulfate may help manage these effects.
CONCLUSION
This case underscores the importance of vigilance and frequent clinical examinations in patients with AOPP to identify subtle early signs of potential complications.
引言
孕期急性有机磷中毒（AOPP）并不常见。当并发早产时，由于缺乏既定指南，会出现治疗困境。
病例介绍
作者描述了一例妊娠33周的19岁初产妇发生AOPP的病例。在治疗过程中，她意外地出现了早产、急产，最终分娩出一个健康的活婴。
讨论
妊娠晚期接触有机磷可能通过过量乙酰胆碱引起的受体过度刺激触发早产，导致子宫过早收缩。阿托品、孕酮和硫酸镁可能有助于控制这些影响。
结论
该病例强调了对AOPP患者保持警惕并进行频繁临床检查以识别潜在并发症细微早期迹象的重要性。
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