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从植物到患者:皮肤病学中特定药用植物的历史视角与综述

From Plant to Patient: A Historical Perspective and Review of Selected Medicinal Plants in Dermatology.

作者信息

Israyilova Aygun, Peykova Tsvetomira Zhivkova, Kittleson Ben, Sprowl Paul Caleb, Mohammed Taha Osman, Quave Cassandra L

机构信息

Department of Dermatology, Emory University School of Medicine, Atlanta, Georgia, USA.

Laboratory of Microbiology, Center of Excellence, Baku State University, Baku, Azerbaijan.

出版信息

JID Innov. 2024 Oct 25;5(1):100321. doi: 10.1016/j.xjidi.2024.100321. eCollection 2025 Jan.

DOI:10.1016/j.xjidi.2024.100321
PMID:39651343
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11625147/
Abstract

Skin conditions are a common health concern faced by patients of all ages. For thousands of years, plants have been used to treat various skin conditions, including acne, vitiligo, and psoriasis, to name a few. Today, with increasing patient preference for natural therapies, modern medicine is now more than ever incorporating age-old knowledge of herbal remedies useful in treating skin conditions into modern-day treatments. This review covers various plant-derived therapeutics (polyphenon E [sincatechins], psoralen, salicylic acid, anthralin, podophyllotoxin, and Filsuvez [birch triterpenes, oleogel-S10]) that have demonstrated scientific evidence of clinical efficacy for dermatologic disorders. The discovery, composition, history of use, and current uses in dermatology are summarized for each botanical ingredient.

摘要

皮肤疾病是各年龄段患者共同面临的健康问题。数千年来,植物一直被用于治疗各种皮肤疾病,痤疮、白癜风和牛皮癣等仅为其中几例。如今,随着患者对自然疗法的偏好增加,现代医学比以往任何时候都更多地将治疗皮肤疾病有用的古老草药知识纳入现代治疗方法中。本综述涵盖了多种植物源治疗剂(表没食子儿茶素没食子酸酯、补骨脂素、水杨酸、蒽林、鬼臼毒素和Filsuvez[桦木三萜、油凝胶-S10]),这些治疗剂已证明对皮肤病具有临床疗效的科学证据。对每种植物成分的发现、成分、使用历史及在皮肤病学中的当前用途进行了总结。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2884/11625147/40bb8d132a58/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2884/11625147/8fc85c8f2d2a/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2884/11625147/1f78aaf5585d/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2884/11625147/18e711b177af/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2884/11625147/bcb36c47b46e/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2884/11625147/768a78f119cd/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2884/11625147/40bb8d132a58/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2884/11625147/8fc85c8f2d2a/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2884/11625147/1f78aaf5585d/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2884/11625147/18e711b177af/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2884/11625147/bcb36c47b46e/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2884/11625147/768a78f119cd/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2884/11625147/40bb8d132a58/gr6.jpg

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Adv Ther. 2024 Feb;41(2):867-877. doi: 10.1007/s12325-023-02749-x. Epub 2024 Jan 3.
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Early Enzymatic Burn Debridement: Results of the DETECT Multicenter Randomized Controlled Trial.早期酶促烧伤清创术:DETECT多中心随机对照试验的结果
J Burn Care Res. 2024 Mar 4;45(2):297-307. doi: 10.1093/jbcr/irad142.
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Birch Bark Extract: A Review in Epidermolysis Bullosa.
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Drugs. 2023 Sep;83(14):1309-1314. doi: 10.1007/s40265-023-01935-z. Epub 2023 Sep 2.
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Pharmacological Potential of Betulin as a Multitarget Compound.桦木醇作为一种多靶点化合物的药理学潜力。
Biomolecules. 2023 Jul 12;13(7):1105. doi: 10.3390/biom13071105.
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Antioxidative and Antimicrobial Evaluation of Bark Extracts from Common European Trees in Light of Dermal Applications.基于皮肤应用对欧洲常见树木树皮提取物的抗氧化和抗菌评估。
Antibiotics (Basel). 2023 Jan 9;12(1):130. doi: 10.3390/antibiotics12010130.
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