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一例酷似重症肌无力的后颅窝病变

A Posterior Cranial Fossa Lesion Mimicking Myasthenia Gravis.

作者信息

Shah Syed Wajihullah, Khalil Maryam, Iqbal Mansoor, Kundi Arham Arif, Hassaan Muhammad

机构信息

Khyber Medical College, Peshawar, Pakistan.

Department of Neurology, Pakistan Institute of Medical Sciences, Islamabad, Pakistan.

出版信息

Eur J Case Rep Intern Med. 2024 Nov 25;11(12):005032. doi: 10.12890/2024_005032. eCollection 2024.

Abstract

UNLABELLED

A 41-year-old male with prior diagnosis of seronegative myasthenia gravis presented with complaints of bilateral ptosis, dysphagia, nasal voice and nasal regurgitation. Despite treatment with pyridostigmine, there was lack of significant improvement in the symptoms. Further investigations, including antibody assays and nerve conduction studies did not support the diagnosis. Magnetic resonance imaging revealed a lesion in the posterior cranial fossa, consistent with meningioma, which was compressing surrounding structures. This case highlights the importance of imaging techniques and considering alternative diagnosis in patients with unusual presentations to ensure appropriate management.

LEARNING POINTS

This case emphasizes the importance of imaging in patients presenting with symptoms similar to those of neuromuscular junction disorders.It also highlights the possible challenges in diagnosis of such patients.

摘要

未标注

一名41岁男性,既往诊断为血清阴性重症肌无力,出现双侧上睑下垂、吞咽困难、鼻音和鼻反流症状。尽管使用吡啶斯的明治疗,但症状仍无明显改善。包括抗体检测和神经传导研究在内的进一步检查不支持该诊断。磁共振成像显示后颅窝有一个病变,符合脑膜瘤,压迫周围结构。该病例强调了成像技术的重要性,以及在表现不寻常的患者中考虑其他诊断以确保适当管理的重要性。

学习要点

该病例强调了成像在出现与神经肌肉接头疾病相似症状患者中的重要性。它还突出了此类患者诊断中可能面临的挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca73/11623349/7a7c4630fa90/5032_Fig1.jpg

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