Effect of infusion time on risk of bloodstream infections in patients administered with BFLUID amino acid infusions via peripheral venous catheters.

Comprehensive electrolyte infusions containing amino acids, including BFLUID, are a source of nosocomial infections caused by . It is recommended that clinicians finish the administration of BFLUID within 6 h; however, this recommendation currently lacks supporting empirical evidence. Accordingly, the present study aimed to investigate the risk of infection associated with BFLUID infusion according to the administration time. In the present single-center retrospective observational cohort study, clinical information was extracted from the medical records of patients aged ≥18 years who received BFLUID infusions via a peripheral line between April 2017 and October 2020 at Saitama Red Cross Hospital (Saitama, Japan). A total of 96 patients were enrolled during the study period, of whom 32 developed infection. No patients with BFLUID infusions administered within 6 h developed infection. Compared with patients who received BFLUID infusions within 8 h, those who received BFLUID infusions after 8 h had a 7-fold higher risk of infection. The present study provided empirical evidence supporting the recommendation that amino acid infusions should be administered to patients within 6 h to minimize the risk of infection.