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子宫内膜异位症的管理:呼吁采取多学科方法。

Management of endometriosis: a call to multidisciplinary approach.

作者信息

Duncan Jordann-Mishael, Delara Ritchie, Ranieri Gina, Wasson Megan

机构信息

Department of Medical and Surgical Gynecology, Mayo Clinic, Phoenix, AZ, USA.

Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Levine Cancer Institute, Atrium Health, Charlotte, NC, USA.

出版信息

J Osteopath Med. 2024 Dec 10;125(6):305-313. doi: 10.1515/jom-2024-0105. eCollection 2025 Jun 1.

Abstract

Endometriosis is defined as the presence of endometrial-like glands and stroma outside of the uterus. There are three types of endometriotic lesions: superficial or peritoneal endometriosis, ovarian endometrioma, and deep infiltrating disease. Endometriosis not only occurs in the pelvis but also can be found in extrapelvic sites such as the gastrointestinal tract, upper abdominal viscera, genitourinary tract, abdominal wall, diaphragm, and thoracic cavity. After thorough history and physical examination is performed, imaging, such as ultrasound or magnetic resonance imaging (MRI), should be obtained if there is high suspicion for deep-infiltrating endometriosis to better assess visceral involvement. Endometriosis can be suspected based on symptoms, physical examination findings, and imaging. However, a definitive diagnosis requires histopathologic confirmation. Treatment options include expectant, medical, and surgical management. Endometriosis is largely a quality-of-life issue, and treatment should be tailored accordingly with empiric medical therapy frequently utilized. Medical management focuses on symptom improvement. Surgical management with excision of endometriosis is preferred over ablation or fulguration of endometriotic lesions. In the case of deep or extrapelvic endometriosis, treatment with a multidisciplinary team with experience in the treatment of advanced-stage endometriosis is essential to minimizing morbidity and increasing long-term success.

摘要

子宫内膜异位症的定义为子宫外出现类似子宫内膜的腺体和间质。子宫内膜异位性病变有三种类型:浅表性或腹膜性子宫内膜异位症、卵巢子宫内膜异位囊肿和深部浸润性病变。子宫内膜异位症不仅发生在盆腔,还可出现在盆腔外部位,如胃肠道、上腹部脏器、泌尿生殖道、腹壁、膈肌和胸腔。在进行全面的病史采集和体格检查后,如果高度怀疑深部浸润性子宫内膜异位症,应进行影像学检查,如超声或磁共振成像(MRI),以更好地评估脏器受累情况。可根据症状、体格检查结果和影像学检查怀疑子宫内膜异位症。然而,明确诊断需要组织病理学证实。治疗选择包括期待治疗、药物治疗和手术治疗。子宫内膜异位症在很大程度上是一个生活质量问题,治疗应相应地进行调整,经验性药物治疗经常被采用。药物治疗侧重于改善症状。手术治疗时,切除子宫内膜异位症优于消融或电灼子宫内膜异位性病变。对于深部或盆腔外子宫内膜异位症,由在晚期子宫内膜异位症治疗方面有经验的多学科团队进行治疗对于将发病率降至最低并提高长期成功率至关重要。

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