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采用附着于顺磁性微粒的抗体通过放射免疫分析法进行五项甲状腺功能测试。

Performance of five thyroid-function tests by radioimmunoassays with antibodies attached to paramagnetic micro-particles.

作者信息

Ng R H, Porter A, Leddy M, Statland B E

出版信息

Clin Chem. 1985 Jan;31(1):87-90.

PMID:3965220
Abstract

We have assessed the analytical and clinical performance of five thyroid-function tests by commercially available radioimmunoassays in which antibodies attached to paramagnetic micro-particles are used (Corning MAGIC assays). We evaluated the methods for measuring thyroxin, triiodothyronine, triiodothyronine uptake, thyrotropin (thyroid-stimulating hormone), and free thyroxin. Precision, patients' results, and clinical correlation of the MAGIC assays were similar to those of the well-established RIAs used as the comparative methods in this study; the MAGIC assays, however, are much faster and easier to perform.

摘要

我们通过使用附着于顺磁性微粒的抗体的市售放射免疫测定法(康宁MAGIC测定法)评估了五项甲状腺功能测试的分析性能和临床性能。我们评估了测量甲状腺素、三碘甲状腺原氨酸、三碘甲状腺原氨酸摄取、促甲状腺激素(甲状腺刺激激素)和游离甲状腺素的方法。MAGIC测定法的精密度、患者结果和临床相关性与本研究中用作比较方法的成熟放射免疫测定法相似;然而,MAGIC测定法执行起来要快得多且更容易。

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