Ben-Shoshan Moshe, Kanani Amin, Kalicinsky Chrystyna, Watson Wade
Division of Pediatric Allergy, Clinical Immunology and Dermatology, Department of Pediatrics, McGill University Health Center, Montreal, QC, Canada.
Division of Allergy and Immunology, Department of Medicine, University of British Columbia, Vancouver, BC, Canada.
Allergy Asthma Clin Immunol. 2024 Dec 9;20(Suppl 3):64. doi: 10.1186/s13223-024-00931-6.
Urticaria (hives) is a common disorder that may be associated with angioedema (swelling that occurs beneath the skin). It is generally classified as acute or chronic, and chronic urticaria is further classified as spontaneous or inducible Second-generation, non-sedating histamine type 1 (H1)-receptor antihistamines represent the mainstay of therapy for both acute and chronic urticaria. Second-line treatment for uncontrolled chronic urticaria includes omalizumab (a monoclonal anti-immunoglobulin E [IgE] antibody). In this article, we review the causes, diagnosis and management of urticaria (with or without angioedema).
荨麻疹(风疹块)是一种常见病症,可能与血管性水肿(发生在皮肤下的肿胀)有关。它通常分为急性或慢性,慢性荨麻疹又进一步分为自发性或诱发性。第二代非镇静性组胺1型(H1)受体抗组胺药是急性和慢性荨麻疹治疗的主要药物。对于控制不佳的慢性荨麻疹,二线治疗包括奥马珠单抗(一种抗免疫球蛋白E [IgE] 单克隆抗体)。在本文中,我们回顾了荨麻疹(伴或不伴血管性水肿)的病因、诊断和管理。