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恶性淋巴瘤患者输尿管淀粉样变性的病例报告(该病例为偶然诊断)

Case report on ureteral amyloidosis that was incidentally diagnosed in a patient with malignant lymphoma.

作者信息

Makihara Yuko, Yoshizako Takeshi, Miyamoto Akina, Yoshida Rika, Wada Koichiro, Kaji Yasushi

机构信息

Department of Radiology, Shimane University, Faculty of Medicine, 89-1 Enya Izumo, Shimane 693-8501, Japan.

Department of Urology, Shimane University, Faculty of Medicine, 89-1 Enya Izumo, Shimane 693-8501, Japan.

出版信息

Radiol Case Rep. 2024 Nov 25;20(2):1014-1017. doi: 10.1016/j.radcr.2024.10.133. eCollection 2025 Feb.

DOI:10.1016/j.radcr.2024.10.133
PMID:39654581
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11626643/
Abstract

Herein, we report a rare case of localized ureteral amyloidosis in a patient with malignant lymphoma. A 73-year-old female patient visited our institution for a comprehensive examination and treatment of malignant lymphoma. Contrast-enhanced computed tomography scan and magnetic resonance imaging revealed left hydronephrosis and a left lower ureteral mass. These findings suggested either ureteral amyloidosis or a ureteral carcinoma with significant fibrosis. Cystoscopic biopsy was performed, and the patient was pathologically diagnosed with ureteral amyloidosis. Renal renography revealed left renal dysfunction. However, the patient was asymptomatic. Hence, the patient should be followed-up for ureteral amyloidosis. Computed tomography scan were performed every 3 months, and after approximately 1 year, there was no evidence of mass enlargement. This case highlights the rarity of ureteral amyloidosis and the importance of imaging diagnosis in clinical practice.

摘要

在此,我们报告一例恶性淋巴瘤患者发生局部输尿管淀粉样变性的罕见病例。一名73岁女性患者因恶性淋巴瘤前来我院进行全面检查和治疗。增强计算机断层扫描和磁共振成像显示左肾积水和左输尿管下段肿块。这些发现提示可能是输尿管淀粉样变性或伴有显著纤维化的输尿管癌。进行了膀胱镜活检,患者经病理诊断为输尿管淀粉样变性。肾动态显像显示左肾功能不全。然而,患者并无症状。因此,应对该患者的输尿管淀粉样变性进行随访。每3个月进行一次计算机断层扫描,大约1年后,没有肿块增大的迹象。该病例凸显了输尿管淀粉样变性的罕见性以及影像诊断在临床实践中的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8ab/11626643/a63e80bc8cae/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8ab/11626643/9a448a38e05f/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8ab/11626643/3b47d97f45df/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8ab/11626643/d3868843f533/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8ab/11626643/a63e80bc8cae/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8ab/11626643/9a448a38e05f/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8ab/11626643/3b47d97f45df/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8ab/11626643/d3868843f533/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8ab/11626643/a63e80bc8cae/gr4.jpg

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本文引用的文献

1
Localized amyloidosis of the ureter: a case report.输尿管局部淀粉样变性:一例报告。
J Med Case Rep. 2023 Oct 8;17(1):443. doi: 10.1186/s13256-023-04138-y.
2
Diagnosis and management of AL amyloidosis due to B-cell non-Hodgkin lymphoma.B细胞非霍奇金淋巴瘤所致AL淀粉样变性的诊断与管理
Front Oncol. 2022 Dec 15;12:915420. doi: 10.3389/fonc.2022.915420. eCollection 2022.
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Utility of 18F-FDG PET(/CT) in patients with systemic and localized amyloidosis.18F-FDG PET(/CT) 在系统性和局限性淀粉样变性患者中的应用。
Eur J Nucl Med Mol Imaging. 2013 Jul;40(7):1095-101. doi: 10.1007/s00259-013-2375-1. Epub 2013 Mar 9.
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Radiological findings of primary localized amyloidosis of the ureter.输尿管原发性局限性淀粉样变性的放射学表现。
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Imaging evaluation of amyloidosis of the urinary tract and retroperitoneum.尿路和腹膜后淀粉样变性的影像学评价。
Radiographics. 2011 Oct;31(6):1569-82. doi: 10.1148/rg.316115519.
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[Case report: a case of localized amyloidosis of the ureter].
Hinyokika Kiyo. 2008 Jun;54(6):419-22.