Alexandru Florian Crisan, Camelia Corina Pescaru, Adelina Maritescu, Vlad Carunta, Roxana Ramona Onofrei, Emil Robert Stoicescu, Cristian Oancea
Department of Rehabilitation, Physical Medicine and Rheumatology, Research Center for Assessment of Human Motion, Functionality, and Disability, "Victor Babes" University of Medicine and Pharmacy Timisoara, Timisoara, Romania.
Pulmonary Rehabilitation Center, Clinical Hospital of Infectious Diseases and Pulmonology, "Victor Babes", Timisoara, Romania.
Ther Adv Respir Dis. 2024 Jan-Dec;18:17534666241287302. doi: 10.1177/17534666241287302.
Chronic obstructive pulmonary disease (COPD) significantly impacts respiratory and motor function, balance, and cognition, leading to muscle weakness and impaired exercise capacity. The impairments often result in challenges with daily activities, particularly those requiring dual-tasking.
The study investigated whether patients with severe COPD would exhibit more significant cognitive and motor performance decline during dual tasks compared to healthy controls.
This study employed a cross-sectional design to compare cognitive and motor performance in dual tasks between patients with severe COPD and healthy controls.
We included 44 patients with severe COPD and 43 healthy individuals. Participants underwent various tests, including pulmonary function tests, six-minute walking tests, dual Timed Up and Go tests (TUG), dual single-leg stance tests (SLS), Berg Balance Scale assessments, and Falls Efficacy Scale International evaluations (FES-I).
The COPD group had significantly lower scores in the Berg Balance Scale (BBS; 44.79 ± 4.70 vs 52.67 ± 2.16, < 0.0001) and longer times for the TUG test (12.44 s; [11.44, 13.50] vs 9.14 s; [7.91, 10.11], < 0.0001) and shorter times for the SLS test (14.15 s; [12.31, 15.65] vs 26.20 s; [23.45, 30.88], < 0.0001), indicating poorer functional mobility and balance. Furthermore, dual-task interference (DTI) outcomes revealed poorer performance in the COPD group ( < 0.0001). The fear of falling (FES-I) was increased in the COPD group. There was a significant positive correlation between DTI TUG and FES-I ( = 0.35, = 0.01) and a negative correlation between DTI SLS and BBS ( = -0.41, = 0.005) in the COPD group.
The study reveals significant impairments in DTI and balance among patients with severe COPD. Patients with severe COPD performed worse in tests involving dual tasks. They had poorer balance overall compared to healthy controls, with longer times for the dual Timed Up and Go test and shorter times for the SLS test, indicating a higher susceptibility to DTI and a greater fear of falling.
慢性阻塞性肺疾病（COPD）对呼吸和运动功能、平衡及认知有显著影响，导致肌肉无力和运动能力受损。这些损害常给日常活动带来挑战，尤其是那些需要同时执行多项任务的活动。
本研究调查重度COPD患者在执行双重任务时，与健康对照相比，是否会表现出更显著的认知和运动能力下降。
本研究采用横断面设计，比较重度COPD患者和健康对照在双重任务中的认知和运动表现。
我们纳入了44例重度COPD患者和43名健康个体。参与者接受了各种测试，包括肺功能测试、六分钟步行测试、双重定时起立行走测试（TUG）、双重单腿站立测试（SLS）、伯格平衡量表评估以及国际跌倒效能量表（FES-I）评估。
COPD组在伯格平衡量表（BBS）中的得分显著更低（44.79±4.70 vs 52.67±2.16，<0.0001），TUG测试用时更长（12.44秒；[11.44，13.50] vs 9.14秒；[7.91，10.11]，<0.0001），SLS测试用时更短（14.15秒；[12.31，15.65] vs 26.20秒；[23.45，30.88]，<0.0001），表明其功能移动性和平衡能力较差。此外，双重任务干扰（DTI）结果显示COPD组表现更差（<0.0001）。COPD组对跌倒的恐惧（FES-I）增加。在COPD组中，DTI TUG与FES-I之间存在显著正相关（=0.35，=0.01），DTI SLS与BBS之间存在负相关（=-0.41，=0.005）。
该研究揭示了重度COPD患者在DTI和平衡方面存在显著损害。重度COPD患者在涉及双重任务的测试中表现更差。与健康对照相比，他们总体平衡能力更差，双重定时起立行走测试用时更长，单腿站立测试用时更短，表明其对DTI的易感性更高，对跌倒的恐惧更大。
