Krämer Manja, Charonis Anastasios, Arba-Mosquera Samuel
J Refract Surg. 2024 Dec;40(12):e1003-e1014. doi: 10.3928/1081597X-20241002-01. Epub 2024 Dec 1.
To present a new approach to customized treatments that inherently saves tissue by design, especially for pathological corneas.
From the elevation of the anterior cornea and the refractive error of the eye, the target cornea can be calculated and the difference between actual and target cornea corresponds to the tissue to be removed. In this approach, it is further possible to preset the ablation depth at one (Model 1) or two (Models 2 and 3) particular locations. In all three models, the target cornea floats in z-direction, until the depth is reached at one of these defined locations. In Model 2, the depth at the second location is reached by modulating the asphericity, whereas in Model 3, asphericity is maintained but average curvature is modulated to achieve the desired depth at the second location. After floating in z-direction, and modulation, locations with a negative ablation value are set to zero (primary clipping). Additionally, locations exceeding a preset maximum ablation depth are set to a predefined depth (secondary clipping).
Simulated cases based on patient diagnosis were used to better explain and illustrate the technique.
With this approach, free-form ablation zones are generated, providing for a tissue-saving correction of refractive error and partial correction of higher order aberrations, the overall corneal shape will be recentered, and the corneal curvature gradient is reduced. .
提出一种定制化治疗的新方法,该方法从设计上就能固有地节省组织,尤其适用于病理性角膜。
根据前角膜的高度和眼睛的屈光不正,可以计算出目标角膜,实际角膜与目标角膜之间的差异对应于要去除的组织。在这种方法中,还可以在一个(模型1)或两个(模型2和3)特定位置预设消融深度。在所有三个模型中,目标角膜在z方向上浮动,直到在这些定义位置之一达到所需深度。在模型2中,通过调整非球面性来达到第二个位置的深度,而在模型3中,保持非球面性,但调整平均曲率以在第二个位置达到所需深度。在z方向上浮动并调整后,将具有负消融值的位置设置为零(一次裁剪)。此外,将超过预设最大消融深度的位置设置为预定义深度(二次裁剪)。
基于患者诊断的模拟病例被用于更好地解释和说明该技术。
通过这种方法,可以生成自由形式的消融区,实现节省组织的屈光不正矫正和高阶像差的部分矫正,整体角膜形状将重新居中,角膜曲率梯度降低。