Ong Anthony, Wilcox Kenneth, Reid M Carrington, Wethington Elaine, Cintron Dakota, Addington Elizabeth, Goktas Selin, Moskowitz Judith
Department of Psychology, Cornell University, Ithaca, NY, United States.
Department of Medicine, Weill Cornell University, NYC, NY, United States.
J Med Internet Res. 2024 Dec 10;26:e54678. doi: 10.2196/54678.
Fibromyalgia is a chronic pain condition characterized by widespread musculoskeletal pain, fatigue, and cognitive difficulties, affecting individuals across all age groups. Positive affect (PA) interventions have shown promise in enhancing emotional well-being and pain management in patients with diverse chronic pain conditions. However, the efficacy of internet-delivered PA interventions for individuals with fibromyalgia remains understudied.
This randomized controlled trial investigated the efficacy of a web-based PA regulation intervention-Lessons in Affect Regulation to Keep Stress and Pain Under Control (LARKSPUR)-in enhancing emotional and functional well-being among adults with fibromyalgia syndrome.
A total of 95 participants with fibromyalgia syndrome aged 50 years and older (89/95, 94% female) were randomized to one of two fully automated conditions: (1) LARKSPUR (n=49) or (2) emotion reporting/attention control (n=46). At the postintervention and 1-month follow-up time points, participants completed 7 consecutive, end-of-day, web-based reports capturing positive events (PE), pain, fatigue, PA, and negative affect.
Compared to control, LARKSPUR resulted in greater improvements in daily affective responsivity to PE at the postintervention time point, including greater reductions in negative affect (b-b=-0.06, 95% highest posterior density interval [HPD] -0.10 to -0.02) and increases in PA (b-b=0.10, 95% HPD 0.02-0.19). Furthermore, across the postintervention and 1-month follow-up time points, LARKSPUR led to greater reductions in pain (b-b=-0.20, 95% HPD -0.36 to -0.04) and fatigue (b-b=-0.24, 95% HPD -0.41 to -0.06) following PE.
This randomized controlled trial provides initial evidence that a web-based PA skills intervention can enhance emotional well-being and reduce pain and fatigue in aging adults with fibromyalgia.
ClinicalTrials.gov NCT04869345; https://clinicaltrials.gov/study/NCT04869345.
纤维肌痛是一种慢性疼痛病症，其特征为广泛的肌肉骨骼疼痛、疲劳和认知困难，影响所有年龄组的个体。积极情绪（PA）干预已显示出有望改善各种慢性疼痛病症患者的情绪健康和疼痛管理。然而，针对纤维肌痛患者的互联网提供的PA干预的疗效仍未得到充分研究。
这项随机对照试验调查了基于网络的PA调节干预——《情绪调节课程以控制压力和疼痛》（LARKSPUR）——对纤维肌痛综合征成年人情绪和功能健康的改善效果。
共有95名年龄在50岁及以上的纤维肌痛综合征参与者（89/95，94%为女性）被随机分配到两种全自动条件之一：（1）LARKSPUR（n = 49）或（2）情绪报告/注意力控制（n = 46）。在干预后和1个月随访时间点，参与者连续7天在每天结束时完成基于网络的报告，记录积极事件（PE）、疼痛、疲劳、PA和消极情绪。
与对照组相比，LARKSPUR在干预后时间点对PE的日常情感反应性有更大改善，包括消极情绪的更大减少（b-b=-0.06，95%最高后验密度区间[HPD] -0.10至-0.02）和PA的增加（b-b=0.10，95% HPD 0.02 - 0.19）。此外，在干预后和1个月随访时间点，LARKSPUR导致PE后疼痛（b-b=-0.20，95% HPD -0.36至-0.04）和疲劳（b-b=-0.24，95% HPD -0.41至-0.06）的更大减少。
这项随机对照试验提供了初步证据，表明基于网络的PA技能干预可以改善纤维肌痛老年成年人的情绪健康，减轻疼痛和疲劳。
ClinicalTrials.gov NCT04869345；https://clinicaltrials.gov/study/NCT04869345。
