Suppr超能文献

后鼻神经手术神经切除术与消融术治疗慢性鼻炎的比较

Posterior nasal nerve surgical neurectomy versus ablation for chronic rhinitis.

作者信息

Maddineni Sainiteesh, Hwang Peter H, Patel Zara M, Nayak Jayakar V, Chang Michael T

机构信息

Department of Otolaryngology - Head & Neck Surgery, Stanford University School of Medicine, Stanford, CA 94305, United States of America.

Department of Otolaryngology - Head & Neck Surgery, Stanford University School of Medicine, Stanford, CA 94305, United States of America.

出版信息

Am J Otolaryngol. 2025 Jan-Feb;46(1):104553. doi: 10.1016/j.amjoto.2024.104553. Epub 2024 Dec 9.

Abstract

INTRODUCTION

For chronic rhinitis (CR) refractory to medical management, several ablative procedures exist that target the posterior nasal nerve (PNN). Here we compare outcomes of PNN surgical neurectomy to in-office ablative procedures.

METHODS

We retrospectively reviewed patients with CR who trialed ipratropium at our center from 2013 to 2024 and received PNN ablation (cryoablation or radiofrequency) or neurectomy. We used the SNOT-22 questionnaire to assess outcomes, specifically evaluating the rhinologic subdomain: need to blow nose, sneezing, runny nose, nasal obstruction, loss of smell, cough, post-nasal discharge, and thick nasal discharge.

RESULTS

Our cohort consisted of 55 patients, 34 receiving PNN ablation and 26 receiving surgical neurectomy (9 receiving both). Mean follow-up time was 243 ± 353 days. Surgical neurectomy (18.6 ± 5.5 to 14.9 ± 5.9, p = 0.02) were associated with significant SNOT-22 rhinologic domain improvements, and neurectomy was associated with significant rhinorrhea improvement (3.4 ± 1.6 to 2.4 ± 1.7, p = 0.04). Surgical neurectomy was associated with a greater decrease in sneezing (p = 0.04) scores than ablation, although there were no significant differences in total or rhinologic subdomain SNOT-22 scores between ablation and neurectomy. No clear improvements were observed in patients undergoing a neurectomy following ablation. Multivariable logistic regression analysis did not reveal any predictors of post-procedure improvement.

CONCLUSION

Both surgical neurectomy and in-office ablation were associated with improvements in rhinologic symptoms for patients with CR, although neurectomy may have increased benefit for specific symptoms like sneezing. There is limited evidence that secondary procedure after an initial ablation is beneficial.

摘要

引言

对于药物治疗无效的慢性鼻炎(CR),有几种针对鼻后神经(PNN)的消融手术。在此,我们比较了PNN手术神经切除术与门诊消融手术的效果。

方法

我们回顾性分析了2013年至2024年在我们中心试用异丙托溴铵并接受PNN消融(冷冻消融或射频消融)或神经切除术的CR患者。我们使用SNOT-22问卷评估结果,特别评估鼻科子领域:擤鼻需求、打喷嚏、流鼻涕、鼻塞、嗅觉丧失、咳嗽、鼻后滴漏和浓稠鼻涕。

结果

我们的队列包括55名患者,34名接受PNN消融,26名接受手术神经切除术(9名同时接受两者)。平均随访时间为243±353天。手术神经切除术(从18.6±5.5降至14.9±5.9,p=0.02)与SNOT-22鼻科领域的显著改善相关,神经切除术与鼻漏的显著改善相关(从3.4±1.6降至2.4±1.7,p=0.04)。手术神经切除术与打喷嚏评分的降低幅度大于消融术相关(p=0.04),尽管消融术和神经切除术之间的SNOT-22总分或鼻科子领域评分没有显著差异。消融术后接受神经切除术的患者未观察到明显改善。多变量逻辑回归分析未发现术后改善的任何预测因素。

结论

手术神经切除术和门诊消融术均与CR患者的鼻科症状改善相关,尽管神经切除术可能对打喷嚏等特定症状有更大益处。初步消融后进行二次手术有益的证据有限。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验