Stiermaier Thomas, Eitel Ingo
University Heart Center Lübeck, Medical Clinic II, Lübeck, Germany and German Center for Cardiovascular Research (DZHK), Partner site Hamburg - Kiel - Lübeck, Lübeck, Germany.
University Heart Center Lübeck, Medical Clinic II, Lübeck, Germany and German Center for Cardiovascular Research (DZHK), Partner site Hamburg - Kiel - Lübeck, Lübeck, Germany.
Trends Cardiovasc Med. 2025 Apr;35(3):197-201. doi: 10.1016/j.tcm.2024.12.002. Epub 2024 Dec 8.
Takotsubo syndrome (TTS) is a condition of acute ventricular dysfunction mainly in aging women that is frequently precipitated by episodes of physical or emotional stress. The association with negative emotional triggers such as fear, grief, or interpersonal conflicts was observed soon after the first description of TTS three decades ago and led to the popular term "broken heart syndrome". However, more recent research shows that TTS can also be provoked by pleasant emotions in some patients, referred to as "happy heart syndrome". This review will discuss the role of stressful triggers in patients with TTS and their impact on the course of the disease with a particular focus on characteristic features of happy heart syndrome.
应激性心肌病（TTS）是一种主要发生于老年女性的急性心室功能障碍疾病，常由身体或情绪应激事件诱发。三十年前首次描述TTS后不久，就观察到其与恐惧、悲伤或人际冲突等负面情绪触发因素有关，这导致了“心碎综合征”这一通俗说法。然而，最近的研究表明，在一些患者中，TTS也可由愉悦情绪诱发，即所谓的“开心心脏综合征”。本综述将讨论应激触发因素在TTS患者中的作用及其对疾病进程的影响，特别关注开心心脏综合征的特征。
