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Chitinase 3-like 1 is neurotoxic in multiple sclerosis patient-derived cortical neurons.

作者信息

Pinteac Rucsanda, Soriano Jordi, Matute-Blanch Clara, Lizcano José M, Duarri Anna, Malhotra Sunny, Eixarch Herena, López Comellas Gloria, Montalban Xavier, Comabella Manuel

机构信息

Servei de Neurologia, Centre d´Esclerosi Múltiple de Catalunya (Cemcat), Institut de Recerca Vall d´Hebron (VHIR), Hospital Universitari Vall d´Hebron, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain.

Center for Networked Biomedical Research on Neurodegenerative Diseases (CIBERNED) - ISCIII, Madrid, Spain.

出版信息

Clin Transl Med. 2024 Dec;14(12):e70125. doi: 10.1002/ctm2.70125.

Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e16/11631566/0abc259c1908/CTM2-14-e70125-g002.jpg

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本文引用的文献

2
Chitinases and chitinase-like proteins as biomarkers in neurologic disorders.
Neurol Neuroimmunol Neuroinflamm. 2020 Dec 8;8(1). doi: 10.1212/NXI.0000000000000921. Print 2021 Jan.
3
Chitinase 3-like 1 is neurotoxic in primary cultured neurons.
Sci Rep. 2020 Apr 28;10(1):7118. doi: 10.1038/s41598-020-64093-2.
4
Chitinase 3-like 1: prognostic biomarker in clinically isolated syndromes.
Brain. 2015 Apr;138(Pt 4):918-31. doi: 10.1093/brain/awv017. Epub 2015 Feb 13.
6
Glycine N-methyltransferase expression in the hippocampus and its role in neurogenesis and cognitive performance.
Hippocampus. 2014 Jul;24(7):840-52. doi: 10.1002/hipo.22274. Epub 2014 Apr 8.
7
Cerebrospinal fluid chitinase 3-like 1 levels are associated with conversion to multiple sclerosis.
Brain. 2010 Apr;133(Pt 4):1082-93. doi: 10.1093/brain/awq035. Epub 2010 Mar 17.

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